Causal Coupling Between Electrophysiological Signals, Cerebral Hemodynamics and Systemic Blood Supply Oscillations in Mayer Wave Frequency Range
| Autor: | Michal Kacprzak, Katarzyna J. Blinowska, Piotr Lachert, Piotr Sawosz, Przemyslaw Pulawski, Adam Liebert, Dariusz Janusek, Jaroslaw Zygierewicz |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male medicine.medical_specialty Computer Networks and Communications Movement Rest Hemodynamics 01 natural sciences Signal 010309 optics 03 medical and health sciences Young Adult 0302 clinical medicine Heart Rate Internal medicine 0103 physical sciences Heart rate medicine Heart rate variability Humans Physics Spectroscopy Near-Infrared Resting state fMRI Brain Electroencephalography General Medicine Brain Waves Electrophysiology Blood pressure Cerebrovascular Circulation Oxyhemoglobins Cardiology Functional near-infrared spectroscopy Female 030217 neurology & neurosurgery |
| Zdroj: | International journal of neural systems. 29(5) |
| ISSN: | 1793-6462 |
| Popis: | The aim of the study was to assess causal coupling between neuronal activity, microvascular hemodynamics and blood supply oscillations in the Mayer wave frequency range. An electroencephalogram, cerebral blood oxygenation changes, an electrocardiogram and blood pressure were recorded during rest and during a movement task. Causal coupling between them was evaluated using directed transfer function, a measure based on the Granger causality principle. The multivariate autoregressive model was fitted to all the signals simultaneously, which made it possible to construct a complete scheme of interactions between the considered signals. The obtained pattern of interactions in the resting state estimated in the 0.05–0.15 Hz band revealed a predominant influence of blood pressure oscillations on all the other variables. Reciprocal connections between blood pressure and heart rate variability time series indicated the presence of feedback loops between these signals. During movement, the pattern of connections did not change dramatically. The number of connections decreased, but the couplings between blood pressure and heart rate variability signal were not significantly changed, and the strong influence of the decreased blood hemoglobin concentration on the oxygenated hemoglobin concentration persisted. For the first time our results provided a comprehensive scheme of interactions between electrical and hemodynamic brain signals, heart rate and blood pressure oscillations. Persistent reciprocal connections between blood pressure and heart rate variability time series suggest possible feedforward and feedback coupling of cardiovascular variables which may lead to the observed oscillations in Mayer wave range. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|