[An autopsy case of rheumatoid arthritis accompanied with acute exacerbation of interstitial pneumonia]
| Autor: | Koichiro Aratake, Kiyoshi Migita, Naoki Matsuoka, Yojiro Kawabe, Hideki Nakamura, Shigenobu Nagataki, Kan Toriyama, Katsumi Eguchi, Kyoji Ichinose, Masahiro Tominaga |
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| Rok vydání: | 1998 |
| Předmět: |
Pathology
medicine.medical_specialty Exacerbation Immunology Anti-Inflammatory Agents Arthritis Cyclosporins Methylprednisolone Arthritis Rheumatoid Fatal Outcome Fibrosis Cyclosporin a Edema medicine Immunology and Allergy Humans Diffuse alveolar damage Lung business.industry General Medicine respiratory system Middle Aged medicine.disease respiratory tract diseases medicine.anatomical_structure Rheumatoid arthritis Acute Disease Disease Progression Drug Therapy Combination Female medicine.symptom business Lung Diseases Interstitial Respiratory Insufficiency Immunosuppressive Agents |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 0911-4300 |
| Popis: | An autopsy case of rheumatoid arthritis (RA) with acute exacerbation of interstitial pneumonia is reported. A 57-year-old woman with longstanding RA was admitted to our hospital because of progressive dyspnea. On chest roentogenogram, diffuse interstitial shadow was confirmed in both lungs. Chest computed tomography (CT) showed diffuse lesion of elevated density of CT level in both lung. She was diagnosed as an acute exacerbation of interstitial pneumonia, and treated by methylpredonisolone pulse therapy (1,000 mg/day). Although cyclosporin A (2 mg/kg/day) was combined to steroid therapy, she was died of progressive respiratory failure. The histological findings of the lung showed extensive fibrosis with alveolar damage associated with hyaline membranes, edema and hemorrhage in alveolar space. |
| Databáze: | OpenAIRE |
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