Cross-sectional pilot study about the liver enzymes profile in type 2 diabetic patients from an Algerian west region: Wilaya of Mostaganem
| Autor: | Mahmoud Belalia, L Belkacemi |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Waist Cross-sectional study Endocrinology Diabetes and Metabolism Aspartate transaminase 030209 endocrinology & metabolism Pilot Projects Type 2 diabetes Gastroenterology Diabetes Complications 03 medical and health sciences 0302 clinical medicine Liver Function Tests Diabetes mellitus Internal medicine Internal Medicine medicine Prevalence Humans 030212 general & internal medicine Aspartate Aminotransferases Cause of death Aged Aged 80 and over biology business.industry Liver Diseases Alanine Transaminase General Medicine gamma-Glutamyltransferase Middle Aged medicine.disease Surgery Cross-Sectional Studies Alanine transaminase Diabetes Mellitus Type 2 Liver Algeria biology.protein Alkaline phosphatase Female business |
| Zdroj: | Diabetesmetabolic syndrome. 10(1 Suppl 1) |
| ISSN: | 1878-0334 |
| Popis: | Aims The magnitude of abnormal liver enzymes profile in type 2 diabetic patients is unknown in Algerian west region even though it counts among liver diseases considered as an important cause of death in type 2 diabetes. The main objective is to assess the prevalence of elevated liver enzymes levels among patients with type 2 diabetes from Algerian west region and to determine associated risk factors. Materials and methods A descriptive cross sectional study was performed on 180 type 2 diabetic patients in whom anthropometric and biochemical parameters were determined. Results Twenty-five patients had abnormal elevated alanine transaminase (ALT) (13.9%) with the gender-wise prevalence being 15.9% ( n = 17) in women and 10.9% ( n = 8) in men. The prevalence of abnormal elevated aspartate transaminase (AST), gamma glutamyl transferase and alkaline phosphatase level was respectively 10% ( n = 18), 6.1% ( n = 11) and 8.9% (16). High waist circumference (OR: 5, CI: 1.04–24.04) and high blood pressure (OR: 4.86, CI: 0.94–25.12) were only associated with elevated AST. Fasting glucose >1.4 g/l were associated both with elevated ALT (OR: 3.03, CI: 0.86–10.67) and AST (OR: 5.7, CI: 1.09–29.8). Conclusion A relatively high prevalence of elevated liver enzymes was found in diabetic patients from west Algeria, especially in female patients. |
| Databáze: | OpenAIRE |
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