A High Prevalence of Intracranial Stenosis in Patients with Coronary Artery Disease and the Diagnostic Value of Transcranial Duplex Sonography

Autor: Jurgita Valaikiene, Gintaras Kalinauskas, Ligita Ryliskyte, Irena Butkuviene, J. Badariene, Jurate Dementaviciene, Arunas Vaitkevicius, Roma Puronaite, Arunas Valaika, Aleksandras Laucevičius
Rok vydání: 2019
Předmět:
Adult
Male
medicine.medical_specialty
Ultrasonography
Doppler
Transcranial
Intracranial stenosis
Population
Constriction
Pathologic
Coronary Artery Disease
Disease
Coronary Angiography
Risk Assessment
Severity of Illness Index
Asymptomatic
Brain Ischemia
Coronary artery disease
03 medical and health sciences
Rotterdam Study
0302 clinical medicine
Predictive Value of Tests
Risk Factors
Prevalence
medicine
Humans
Prospective Studies
Ultrasonography
Doppler
Color
education
Aged
Aged
80 and over
education.field_of_study
business.industry
Rehabilitation
Lithuania
Middle Aged
Intracranial Arteriosclerosis
medicine.disease
Stroke
Asymptomatic Diseases
Duplex sonography
Female
Surgery
Neurology (clinical)
Radiology
medicine.symptom
Cardiology and Cardiovascular Medicine
business
030217 neurology & neurosurgery
Calcification
Zdroj: Journal of Stroke and Cerebrovascular Diseases. 28:1015-1021
ISSN: 1052-3057
DOI: 10.1016/j.jstrokecerebrovasdis.2018.12.023
Popis: According to the data from the population-based Rotterdam study, intracranial carotid artery calcification detected by computed tomography is very common and contributed to 75% of all strokes. The aim of the present study was to estimate the prevalence of intracranial stenosis (IS) using noninvasive transcranial color-coded duplex sonography (TCCS) in neurologically asymptomatic patients with coronary artery disease (CAD).Three hundred and eighty-nine patients with angiographically-confirmed, severe CAD were included prospectively. All of them were examined using extracranial and TCCS.Out of 389 patients (age 66.7 ± 9.2, 39-88), 237 (61%) were diagnosed with 3 vessels disease and 152 patients (39%) with left stem disease with/without 3 vessels damage. Transcranial sonography revealed at least 1 IS in 63.6% of echo positive patients (220/346). IS was found in 127 (61.4%) patients with 3 vessels disease, 20 patients (58.8%) with isolated left stem disease, and 73 patients (69.5%) with 3 vessels and left stem disease (P = .305). In the case of significant (≥50%) extracranial internal carotid artery stenosis, intracranial stenosis were detected in 84.8% (50 of 59), in the case of mild (50%) stenosis, in 59.2% (170 of 287), P.001.It was found that two thirds of patients with advanced CAD have a silent IS. TCCS is a reliable method for the evaluation of intracranial atherosclerosis in such patients in order to gain useful information about cerebrovascular disease as a risk factor for stroke.
Databáze: OpenAIRE
Externí odkaz: