Epithelioid pituicytoma: An unusual case report
| Autor: | Matheus Fernandes de Oliveira, Eduardo Vellutini, Luís Felipe Silva Godoy, Pedro Henrique Petit Becker, Nicolau Faria Correia Guerreiro, Romulo Loss Mattedi |
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| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Neuro-Oncology: Case Report Visual acuity 030209 endocrinology & metabolism Lesion 03 medical and health sciences 0302 clinical medicine Brain neoplasm Eosinophilic medicine medicine.diagnostic_test business.industry Magnetic resonance imaging medicine.disease Neurovascular bundle pathology Surgery Histopathology Neurology (clinical) Radiology medicine.symptom business pituicytoma treatment 030217 neurology & neurosurgery Pituicytoma |
| Zdroj: | Surgical Neurology International |
| ISSN: | 2152-7806 |
| DOI: | 10.4103/sni.sni_319_17 |
| Popis: | Background Pituicytomas are considered World Health Organization Grade I malignancies. Until September 2017, a total of 81 cases of pituicytomas were diagnosed and described in literature. We present such a case in which histopathology shows an epithelioid pattern, a rare variant of pituicytoma. As far as we know, this is only the second such case described in the literature. Case description A 61-year-old male patient presented with complaints of progressive decrease in visual acuity for about 7 months, worse on the left side. Laboratory and endocrinological investigation returned normal values. Magnetic resonance imaging revealed a mixed solid-cystic lesion, measuring about 3.1 × 2.2 × 2.9 cm. The lesion presented with intermediate signal intensity in T1 and T2 sequences and showed avid postcontrast enhancement. The patient underwent resection through a left pterional approach. Pathology revealed a glial neoplasm with an epithelioid pattern and moderate cellularity with rounded-elongated cell nuclei and with a broad eosinophilic cytoplasm. Absence of cellular pleomorphism, any mitotic figures, or areas of necrosis was noted. Conclusion The epithelioid variant of pituicytomas differs from the commonly encountered forms of this tumor which typically present in a fascicular pattern. Microsurgical resection is the treatment of choice. However, in many cases, subtotal resection was performed because of a considerable risk for neurovascular injuries. |
| Databáze: | OpenAIRE |
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