How did you know you got the right pill? Prescription opioid identification and measurement error in the abuse deterrent formulation era

Autor: Stephen F. Butler, Eileen Mack Thorley, Priyanka Garg, Traci C. Green, Theresa A. Cassidy, Courtney Kaczmarsky, Carolyn Griffel, Taryn M. Dailey
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Addiction Science & Clinical Practice
ISSN: 1940-0640
1940-0632
Popis: Background Self-report of nonmedical prescription opioid use (NMPU) is a cornerstone of drug abuse surveillance, policymaking, and treatment service planning, but misclassification creates bias and may confuse or undermine NMPU estimates [1]. We detected old OxyContin (OC) abuse reports long after a reformulated version (OP) was released (August 2010). This study explored sources of possible NMPU misclassification and proposed solutions. Materials and methods A mixed-methods approach identified demographic, behavioral, and cognitive factors influencing endorsement of old formulations in: a) multivariable regression analyses of NMPU data from the ASI-MV surveillance program [2] examined predictors of endorsing old (vs. new) formulations during the post-reformulation period (n = 8032); b) prevalence estimates of OC availability from an online recreational drug user forum survey (fall 2013; n = 459); and c) semistructured interviews (n = 29) and cognitive interviews (n = 7) among residential and outpatient substance abuse treatment program clients reporting past 2-year use of OC/OP. A coding guide identified patterns and themes of misidentification in transcribed interviews.
Databáze: OpenAIRE
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