Repeated stress enhances vasopressin synthesis in corticotropin releasing factor neurons in the paraventricular nucleus
| Autor: | Dimphena C.E. de Goeij, F.J.H. Tilders, Daniela Jezova |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Male
Restraint Physical endocrine system medicine.medical_specialty Vasopressin Corticotropin-Releasing Hormone Immunocytochemistry Central nervous system Stress Physiological Parvocellular cell Internal medicine medicine Animals Molecular Biology Neurons Chemistry General Neuroscience Colocalization Rats Inbred Strains Immunohistochemistry Rats Arginine Vasopressin Endocrinology medicine.anatomical_structure nervous system Hypothalamus Neurology (clinical) Nucleus hormones hormone substitutes and hormone antagonists Paraventricular Hypothalamic Nucleus Developmental Biology |
| Zdroj: | Brain Research. 577:165-168 |
| ISSN: | 0006-8993 |
| DOI: | 10.1016/0006-8993(92)90552-k |
| Popis: | The effect of repeated stress on corticotropin-releasing factor (CRF) and vasopressin (AVP) synthesis in parvocellular neurons of the paraventricular nucleus (PVN) was studied by means of double label immunocytochemistry. Once daily immobilization of male rats for 16 days leads to a 75% increase in the number of CRF immunoreactive neurons, but a 5-fold elevation in the number of AVP containing CRF cell bodies. These results demonstrate that repeated stress activates AVP synthesis in CRF neurons. |
| Databáze: | OpenAIRE |
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