Magnetic Resonance Imaging of the Small Bowel in Crohn’s Disease: A Systematic Review and Meta-Analysis
| Autor: | Geoffrey C. Nguyen, Osman S. Ahmed, David M. Rodrigues |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Review Article Disease Sensitivity and Specificity Gastroenterology 030218 nuclear medicine & medical imaging Young Adult 03 medical and health sciences 0302 clinical medicine Text mining Crohn Disease Internal medicine Intestine Small medicine Humans lcsh:RC799-869 Young adult Aged Aged 80 and over Crohn's disease Hepatology medicine.diagnostic_test business.industry Magnetic resonance imaging General Medicine Middle Aged medicine.disease Magnetic Resonance Imaging Confidence interval Stenosis Meta-analysis Female lcsh:Diseases of the digestive system. Gastroenterology 030211 gastroenterology & hepatology business |
| Zdroj: | Canadian Journal of Gastroenterology and Hepatology, Vol 2016 (2016) Canadian Journal of Gastroenterology & Hepatology |
| ISSN: | 2291-2797 2291-2789 |
| DOI: | 10.1155/2016/7857352 |
| Popis: | Introduction. Crohn’s disease is most commonly found in the terminal ileum and colonic region. Magnetic resonance has become a useful modality for assessing small bowel activity. In this study, we performed a systematic review and meta-analysis on the use of MR in detecting small bowel activity as well as extramural complications in Crohn’s patients.Methods. Two independent reviewers sorted through articles until October 2, 2014. We included both studies providing raw data for pooling and studies without raw data. Sensitivity, specificity, likelihood ratios, and 95% confidence intervals were calculated for each study.Results. There were 27 included studies, of which 19 were included in the pooled analysis. Pooled analysis of the 19 studies (1020 patients) with raw data revealed a sensitivity of 0.88 (95% CI 0.86 to 0.91) and specificity was 0.88 (95% CI 0.84 to 0.91). In regard to detecting stenosis, pooled sensitivity was 0.65 (95% CI 0.53 to 0.76) and specificity was 0.93 (95% CI 0.89 to 0.96).Conclusion. MR imaging provides a reliable alternative in detecting small bowel activity in patients with Crohn’s disease. Its advantages include high diagnostic accuracy and no radiation exposure while its disadvantages include high cost and limited availability. |
| Databáze: | OpenAIRE |
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