Oxidative Stress and Endoplasmic Reticulum Stress in Rare Respiratory Diseases

Autor:	María Magallón, Sara Pastor, Ana Carrión, Lucía Bañuls, Daniel Pellicer, Silvia Castillo, Sergio Bondía, María Navarro-García, Cruz González, Francisco Dasí
Rok vydání:	2021
Předmět:	0301 basic medicine Pathology medicine.medical_specialty lcsh:Medicine primary ciliary dyskinesia Review rare respiratory diseases medicine.disease_cause Cystic fibrosis cystic fibrosis 03 medical and health sciences Idiopathic pulmonary fibrosis 0302 clinical medicine otorhinolaryngologic diseases medicine oxidative stress Respiratory system Primary ciliary dyskinesia Alpha 1-antitrypsin deficiency business.industry Endoplasmic reticulum lcsh:R General Medicine idiopathic pulmonary fibrosis medicine.disease respiratory tract diseases 030104 developmental biology Alpha-1 antitrypsin deficiency 030220 oncology & carcinogenesis endoplasmic reticulum stress antioxidant therapies business Oxidative stress
Zdroj:	Journal of Clinical Medicine Journal of Clinical Medicine, Vol 10, Iss 1268, p 1268 (2021)
ISSN:	2077-0383
DOI:	10.3390/jcm10061268
Popis:	Several studies have shown that some rare respiratory diseases, such as alpha-1 antitrypsin deficiency (AATD), idiopathic pulmonary fibrosis (IPF), cystic fibrosis (CF), and primary ciliary dyskinesia (PCD) present oxidative stress (OS) and endoplasmic reticulum (ER) stress. Their involvement in these pathologies and the use of antioxidants as therapeutic agents to minimize the effects of OS are discussed in this review.
Databáze:	OpenAIRE
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