Validation of a novel stand-alone software tool for image guided cardiac catheter therapy
| Autor: | E.R. Nieuwenhuis, Frebus J. van Slochteren, René van Es, Adriaan O. Kraaijeveld, Leon de Jong, Hans T. van den Broek, Steven A. J. Chamuleau, Pieter A. Doevendans, Mira van der Naald |
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| Přispěvatelé: | Magnetic Detection and Imaging |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Cardiac Catheterization
Time Factors Sus scrofa Myocardial Infarction Infarction Contrast Media 030204 cardiovascular system & hematology Pre-clinical research Arrhythmias Magnetic Resonance Imaging Interventional Radiography Interventional Myocardial Infarction/diagnostic imaging Coronary Angiography Multimodal Imaging 030218 nuclear medicine & medical imaging Imaging 0302 clinical medicine Interventional/methods Occlusion Three-Dimensional/methods Clinical endpoint Computer-Assisted/methods Medicine Fluoroscopy Contrast Media/administration & dosage Cardiac imaging Image guided therapy medicine.diagnostic_test Magnetic Resonance Imaging Catheter Imaging Three-Dimensional/methods Radiology Nuclear Medicine and imaging Myocardial viability imaging Female Electrophysiologic Techniques Electrophysiologic Techniques Cardiac Cardiology and Cardiovascular Medicine Cardiac Cardiac/etiology MRI Image-Guided Therapy Magnetic Resonance Imaging Interventional/methods Arrhythmias Cardiac/etiology Injections 03 medical and health sciences Imaging Three-Dimensional Radiography Interventional/methods Predictive Value of Tests Image Interpretation Computer-Assisted Journal Article Animals Radiology Nuclear Medicine and imaging Validation Studies Innovation Image Interpretation Original Paper business.industry Animal Image Interpretation Computer-Assisted/methods Reproducibility of Results Arrhythmias Cardiac Gold standard (test) medicine.disease Radiography Disease Models Animal Hybrid imaging Disease Models Cardiac Catheterization/adverse effects business Nuclear medicine Software |
| Zdroj: | The International Journal of Cardiovascular Imaging, 35(2), 225. Springer Netherlands The International Journal of Cardiovascular Imaging International journal of cardiovascular imaging, 35(2), 225-235. Springer |
| ISSN: | 1569-5794 |
| Popis: | Comparison of the targeting accuracy of a new software method for MRI-fluoroscopy guided endomyocardial interventions with a clinically available 3D endocardial electromechanical mapping system. The new CARTBox2 software enables therapy target selection based on infarction transmurality and local myocardial wall thickness deduced from preoperative MRI scans. The selected targets are stored in standard DICOM datasets. Fusion of these datasets with live fluoroscopy enables real-time visualization of MRI defined targets during fluoroscopy guided interventions without the need for external hardware. In ten pigs (60–75 kg), late gadolinium enhanced (LGE) MRI scans were performed 4 weeks after a 90-min LAD occlusion. Subsequently, 10–16 targeted fluorescent biomaterial injections were delivered in the infarct border zone (IBZ) using either the NOGA 3D-mapping system or CARTBox2. The primary endpoint was the distance of the injections to the IBZ on histology. Secondary endpoints were total procedure time, fluoroscopy time and dose, and the number of ventricular arrhythmias. The average distance of the injections to the IBZ was similar for CARTBox2 (0.5 ± 3.2 mm) and NOGA (− 0.7 ± 2.2 mm; p = 0.52). Injection procedures with CARTBox2 and NOGA required 69 ± 12 and 60 ± 17 min, respectively (p = 0.36). The required endocardial mapping procedure with NOGA prior to injections, leads to a significantly longer total procedure time (p |
| Databáze: | OpenAIRE |
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