Effects of nicardipine on left ventricular dimensions and hemodynamics in systemic hypertension
| Autor: | Sirri Kes, Erdem Oram, Aysel Oram, Şevket Uǧurlu, Çigdem Gökçe |
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| Rok vydání: | 1990 |
| Předmět: |
Male
medicine.medical_specialty Time Factors medicine.medical_treatment Nicardipine Hemodynamics Vasodilation Essential hypertension Coronary artery disease Internal medicine Medicine Humans Chemotherapy Clinical Trials as Topic business.industry Vascular disease Middle Aged medicine.disease Myocardial Contraction Echocardiography Doppler Echocardiography Heart failure Anesthesia Hypertension Cardiology Female Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | The American journal of cardiology. 65(9) |
| ISSN: | 0002-9149 |
| Popis: | Nicardipine is a new calcium antagonist with potent vasodilatory action.1 The improvement of cardiac hemodynamics in animals2 is 1 example of the many promising properties of this drug, which will expectedly lead to its increasing use for the treatment of many cardiovascular disorders, ranging from hypertension to heart failure and from coronary to peripheral vascular disease. Preliminary human trials have also demonstrated an increase of the cardiac pumping ability in subjects with normotension,3 hypertension,4 heart failure5 and coronary artery disease,6 but most of them have evaluated the short-term effects occurring immediately after the parenteral administration of nicardipine. The aim of this echo-cardiographic study was to determine the influence of long-term oral nicardipine therapy on cardiac dimensions and hemodynamics in patients with mild to moderate essential hypertension. |
| Databáze: | OpenAIRE |
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