Experimental Periodontitis in the Potentialization of the Effects of Immobilism in the Skeletal Striated Muscle
| Autor: | Rose Meire Costa Brancalhão, Camila Mayumi Martin Kakihata, Bruna Martinazzo Bortolini, Pedro Henrique de Carli Rodrigues, Gladson Ricardo Flor Bertolini, Marcela Aparecida Leite, Patricia Oehlmeyer Nassar, Lucinéia de Fátima Chasko Ribeiro, Carlos Augusto Nassar, Tatiane Morgenstern de Mattia |
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| Rok vydání: | 2017 |
| Předmět: |
Muscle tissue
medicine.medical_specialty Immunology Connective tissue Inflammation Sarcomere Nociceptive Pain Immobilization 03 medical and health sciences Grip strength 0302 clinical medicine Internal medicine medicine Animals Immunology and Allergy Muscle Strength Rats Wistar Muscle Skeletal Periodontitis Soleus muscle business.industry 030206 dentistry Anatomy medicine.disease Muscle atrophy Muscular Atrophy Endocrinology medicine.anatomical_structure medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Inflammation. 40:2000-2011 |
| ISSN: | 1573-2576 0360-3997 |
| DOI: | 10.1007/s10753-017-0640-3 |
| Popis: | This study aims to evaluate if ligature-induced periodontitis can potentiates the deleterious effects of immobilization in the skeletal striated muscle, contributing to the development of muscle atrophy due to disuse. Forty Wistar rats were divided into four groups: (1) Control Group (CG), (2) Periodontal Disease (PDG), (3) Immobilized (IG), and (4) Immobilized with Periodontal Disease (IPDG). Periodontal disease was induced for 30 days, with ligature method, and the immobilization was performed with cast bandage for 15 days. Prior to euthanasia, nociceptive threshold and muscular grasping force were evaluated. Afterwards, the soleus muscle was dissected and processed for sarcomere counting and morphological/morphometric analysis. For data analysis, was used the one-way ANOVA and post-test Tukey (p |
| Databáze: | OpenAIRE |
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