Heterogeneity in the Definition and Clinical Characteristics of Dumping Syndrome: a Review of the Literature
| Autor: | Guy Hubens, Philip Plaeke, Niels Komen, Ben Gys, Bas Lamme, Anthony Beunis, Thierry Lafullarde |
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| Rok vydání: | 2019 |
| Předmět: |
Pediatrics
medicine.medical_specialty Consensus Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism Hypoglycemia Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Surveys and Questionnaires Terminology as Topic medicine Humans Clinical Trials as Topic Nutrition and Dietetics business.industry medicine.disease Obesity Morbid Clinical Practice Clinical trial Diagnostic Techniques Digestive System Dumping Syndrome Practice Guidelines as Topic Treatment strategy 030211 gastroenterology & hepatology Surgery Dumping syndrome Human medicine business Scientific reporting |
| Zdroj: | Obesity surgery |
| ISSN: | 1708-0428 0960-8923 |
| Popis: | Background No real consensus regarding the definition of dumping syndrome (DS) seems to exist and few subtyping is used in clinical practice. Knowledge is needed for correct design of trials and establishment of uniform treatment strategies. The aim of this study is to explore the distribution of clinical characteristics related to the subtypes of DS. Methods A comprehensive search was performed in Cochrane, Google Scholar, PubMed, and ResearchGate. Data were collected on the definition and diagnostics of DS used in each study. Results Twenty-seven clinical trials were included. Seventeen articles clearly provided a definition of DS and ten of these differentiated between early and late DS. Diagnose of DS was based on clinical symptoms (24 articles), hemodynamic parameters (e.g., tachycardia, hypotension; 9 articles), and biochemical analysis (e.g., blood sugar level; 12 articles). Questionnaires were used in 13 articles. A total of 67 different symptoms were correlated with dumping syndrome. Two symptoms were exclusively correlated with early and nine with late DS. Nine articles differentiated between early and late dumping based on timing since the last meal. Hypoglycemia was correlated with late DS in ten articles. Conclusions This study reveals a vast heterogeneity in the definition and clinical characteristics of DS after RYGB. We feel that a standardized definition is required to provide a firm parameter in the evaluation and setup of clinical trials. A better understanding and description of the definition and diagnostic criteria of DS after RYGB is crucial to improve scientific reporting. |
| Databáze: | OpenAIRE |
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