Cardiovascular and metabolic responses during growth hormone treatment of lactating sheep
| Autor: | Peter D. Gluckman, T. Ben Mepham, Ian C. Hart, R. Brian Heap, Ivan R. Fleet, Frances M. Fullerton |
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| Rok vydání: | 1988 |
| Předmět: |
Blood Glucose
medicine.medical_specialty Pretreatment Period medicine.medical_treatment Injections Subcutaneous Mammary gland Acetates Growth hormone Mammary Glands Animal Pregnancy Internal medicine medicine Animals Lactation Bovine somatotropin Amino Acids chemistry.chemical_classification Sheep Growth factor Hemodynamics General Medicine Amino acid Respiratory quotient Growth hormone treatment Endocrinology medicine.anatomical_structure chemistry Growth Hormone Animal Science and Zoology Female Blood Gas Analysis Food Science |
| Zdroj: | The Journal of dairy research. 55(4) |
| ISSN: | 0022-0299 |
| Popis: | SummaryPituitary-derived bovine growth hormone (bGH) was administered to six lactating Friesland ewes for 7 d. There was no consistent galactopoietic response, with changes in milk yield varying from 0 to 33% during treatment compared with the pretreatment period. The major effect of bGH on the concentration of milk constituents was to increase fat by 14·2% (P < 0·05). Treatment resulted in significant increases in arterial plasma concentrations of growth hormone, insulin-like growth factor I and glucose, with decreases in the plasma arterial concentrations of acetate and certain amino acids. There was a marked reduction in haematocrit and in haemoglobin concentration which took at least 3 d to recover. The arterio-venous difference across the mammary gland decreased for O2 during treatment and the veno-arterial difference for CO2 decreased after treatment. Mammary respiratory quotient therefore decreased significantly after bGH treatment. The results suggest that bGH exerts effects at a number of separate loci. |
| Databáze: | OpenAIRE |
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