Cognitive Impairment Caused by Isolated Adrenocorticotropic Hormone Deficiency without Other Hypo-adrenalism Signs - Autoimmune Encephalopathy Mimics
| Autor: | Takashi Kanda, Motoharu Kawai, Mariko Oishi, Michiaki Koga, Kinya Matsuo |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Thyroiditis medicine.medical_specialty Hydrocortisone Hormone Replacement Therapy Case Report Hashimoto Disease Adrenocorticotropic hormone isolated adrenocorticotropic hormone deficiency Endocrine System Diseases Autoimmune Diseases Diagnosis Differential Adrenocorticotropic Hormone Anterior pituitary Internal medicine Internal Medicine medicine Adrenal insufficiency Humans Cognitive Dysfunction Secretion Chronic thyroiditis cognitive impairment Brain Diseases anti-thyroid antibody business.industry Genetic Diseases Inborn Electroencephalography General Medicine Middle Aged medicine.disease Hypoglycemia Anti-thyroid autoantibodies Endocrinology medicine.anatomical_structure autoimmune encephalopathy Encephalitis Adrenocorticotropic hormone deficiency business Hormone |
| Zdroj: | Internal Medicine |
| ISSN: | 1349-7235 0918-2918 |
| DOI: | 10.2169/internalmedicine.3234-19 |
| Popis: | Isolated adrenocorticotropic hormone deficiency (IAD) is a cause of adrenal insufficiency (AI), which shows impaired secretion of adrenocorticotropic hormone (ACTH) with the preserved secretion of other anterior pituitary gland hormones. We herein report a case of IAD complicated by chronic thyroiditis presenting with neuropsychiatric symptoms without other signs indicative of AI that showed complete improvement of the cognitive function after the administration of corticosteroids. The clinical features of our case may be confused with autoimmune encephalopathies (AEs); however, IAD should be strictly differentiated from AEs, as it requires permanent hormone replacement without addition of immunosuppressive agents. |
| Databáze: | OpenAIRE |
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