Mediterranean Diet, Lifestyle Factors, and 10-year Mortality in Elderly European Men and Women. The HALE Project
| Autor: | Kim T. B. Knoops, Alessandro Menotti, Lisette C. P. G. M. de Groot, Wija A. van Staveren, Daan Kromhout, O. Moreiras-Varela, Anne-Elisabeth Perrin |
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| Jazyk: | angličtina |
| Rok vydání: | 2004 |
| Předmět: |
Male
Gerontology Mediterranean diet Nutrition and Disease Health Behavior Coronary Disease Diet Mediterranean prevention Risk Factors Neoplasms Voeding en Ziekte Epidemiology Longitudinal Studies older men physical-activity risk-factors Cause of death Human Nutrition & Health Aged 80 and over education.field_of_study Mortality rate Smoking Humane Voeding & Gezondheid General Medicine cohort Europe health behaviors Cardiovascular Diseases Cohort Female Cohort study medicine.medical_specialty Alcohol Drinking Population survival medicine Humans Mortality education Exercise Life Style smoking-cessation Aged Proportional Hazards Models VLAG Global Nutrition Wereldvoeding business.industry questionnaire Health Surveys Attributable risk business coronary-heart-disease Demography |
| Zdroj: | JAMA: The Journal of the American Medical Association 292 (2004) 12 JAMA: The Journal of the American Medical Association, 292(12), 1433-1439 |
| ISSN: | 0098-7484 |
| Popis: | Context Dietary patterns and lifestyle factors are associated with mortality from all causes, coronary heart disease, cardiovascular diseases, and cancer, but few studies have investigated these factors in combination. Objective To investigate the single and combined effect of Mediterranean diet, being physically active, moderate alcohol use, and nonsmoking on all-cause and cause-specific mortality in European elderly individuals. Design, Setting, and Participants The Healthy Ageing: a Longitudinal study in Europe (HALE) population, comprising individuals enrolled in the Survey in Europe on Nutrition and the Elderly: a Concerned Action (SENECA) and the Finland, Italy, the Netherlands, Elderly (FINE) studies, includes 1507 apparently healthy men and 832 women, aged 70 to 90 years in 11 European countries. This cohort study was conducted between 1988 and 2000. Main Outcome Measures Ten-year mortality from all causes, coronary heart disease, cardiovascular diseases, and cancer. Results During follow-up, 935 participants died: 371 from cardiovascular diseases, 233 from cancer, and 145 from other causes; for 186, the cause of death was unknown. Adhering to a Mediterranean diet (hazard ratio [HR], 0.77; 95% confidence interval [CI], 0.68-0.88), moderate alcohol use (HR, 0.78; 95% Cl, 0.67-0.91), physical activity (HR, 0.63; 95% Cl, 0.55-0.72), and nonsmoking (HR, 0.65; 95% Cl, 0.57-0.75) were associated with a lower risk of all-cause mortality (HRs controlled for age, sex, years of education, body mass index, study, and other factors). Similar results were observed for mortality from coronary heart disease, cardiovascular diseases, and cancer. The combination of 4 low risk factors lowered the all-cause mortality rate to 0.35 (95% Cl, 0.28-0.44). In total, lack of adherence to this low-risk pattern was associated with a population attributable risk of 60% of all deaths, 64% of deaths from coronary heart disease, 61% from cardiovascular diseases, and 60% from cancer. Conclusion Among individuals aged 70 to 90 years, adherence to a Mediterranean diet and healthful lifestyle is associated with a more than 50% lower rate of all-causes and cause-specific mortality. |
| Databáze: | OpenAIRE |
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