Three-dimensional simultaneous strain–volume analysis describes left ventricular remodelling and its progression: a pilot study
| Autor: | Massimo Magnacca, Rosa Poddighe, Giancarlo Casolo, Marco Tullio Baratto, Alessio Lilli, Alessandro Comella, Carla Svetlich, Andrea Ghidini Ottonelli, Jacopo Del Meglio, Marco Chioccioli |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Cardiomyopathy
Dilated Male medicine.medical_specialty Time Factors Diastole Echocardiography Three-Dimensional Pilot Projects Speckle strain Severity of Illness Index Statistics Nonparametric Ventricular Function Left Internal medicine 3D-echocardiography Medicine Humans Radiology Nuclear Medicine and imaging Systole Ischemic cardiomyopathy Ejection fraction Chi-Square Distribution Cardiac cycle Strain (chemistry) business.industry Infiltrative cardiomyopathy Remodelling Stroke Volume General Medicine Stroke volume Middle Aged Cardiology Disease Progression Female Hypertrophy Left Ventricular Clinical/Original Papers Cardiology and Cardiovascular Medicine business |
| Zdroj: | European Journal of Echocardiography |
| ISSN: | 1532-2114 1525-2167 |
| Popis: | Aims Three-dimensional (3D)-echocardiography speckle imaging allows the evaluation of frame-by-frame strain and volume changes simultaneously. The aim of the present investigation was to describe the strain–volume combined assessment in different patterns of cardiac remodelling. Methods and results Fifty patients received a 3D acquisition. Patients were classified as follows: healthy subjects (CNT), previous AMI, and normal ejection fraction (EF; group A); ischaemic cardiomyopathy with reduced EF (group B); hypertrophic/infiltrative cardiomyopathy (group C). Values of 3D strain were plotted vs. volume for each frame to build a strain–volume curve for each case. Peak of radial, longitudinal, and circumferential systolic strain (Rɛp, Lɛp, and Cɛp, respectively), slopes of the curves (RɛSl, LɛSl, CɛSl), and strain to end-diastolic volume (EDV) ratio (Rɛ/V, Lɛ/V, Cɛ/V) were computed for the analysis. Strain–volume curves of the CNT group were steep and clustered, whereas, due to progressive dilatation and reduction of strains, progressive flattening could be demonstrated in groups A and B. Quantitative data supported visual assessment with progressive lower slopes ( P < 0.05 for RɛSl, CɛSl, P = 0.06 for LɛSl) and significantly lower ratios ( P < 0.01 for Rɛ/V, Lɛ/V, and Cɛ/V). Group C showed an opposite behaviour with slopes and ratios close to those of normal subjects. Correlation coefficients between EDV and slopes of the curves were significant for all the directions of strain (CɛSl: r = 0.891; RєSl: r = 0.704; LєSl: r = 0.833; P < 0.0001 for all). Conclusion We measured left ventricular volumes and strain by 3D-echo and obtained strain–volume curve to evaluate their behaviour in remodelling. A distinctive and progressive pattern consistent with pathophysiology was observed. The analysis here shown could represent a new non-invasive method to assess myocardial mechanics and its relationship with volumes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|