Omaezallene from Red AlgaLaurenciasp.: Structure Elucidation, Total Synthesis, and Antifouling Activity

Autor: Yukihiko Serisawa, Minoru Suzuki, Kazuyo Matsuyama-Serisawa, Hiroshi Matsuura, Taiki Umezawa, Fuyuhiko Matsuda, Yasuyuki Nogata, Yuko Oguri, Shohei Yamazaki, Erina Yoshimura, Takeshi Furuta, Masahiro Suzuki, Tatsufumi Okino, Tsuyoshi Abe
Rok vydání: 2014
Předmět:
Zdroj: Angewandte Chemie. 126:3990-3993
ISSN: 0044-8249
DOI: 10.1002/ange.201311175
Popis: Natural antifouling products have been the subject of considerable attention. We screened marine algae for antifouling activity and discovered omaezallenes, the new bromoallene-containing natural products isolated from the red alga Laurencia sp. Described is the isolation, structure elucidation, and total syntheses of omaezallenes. The relative and absolute configurations of natural omaezallenes were unambiguously established through total synthesis. The antifouling activities and ecotoxicity of omaezallenes were also evaluated.
Databáze: OpenAIRE