| Autor: |
Shao-yong Zhu, Tao Wang, Ping-Yan Chen, Yong Liu, Wei-jie Guan, Li Wei, Zhengyi Ni, David S.C. Hui, Ya-hua Hu, Guang Zeng, Jian-ming Wang, Yi-xiang Peng, Zi-jing Liang, Wenhua Liang, Gang Li, Jinlin Wang, Chang-jiang Ye, Chunliang Lei, Lei Liu, Ruchong Chen, Chun-Quan Ou, Hong Shan, Peng Peng, Jianxing He, Zhi-jian Zheng, Zhong Chen, Chun-Li Tang, Lanjuan Li, Ji-yang Liu, Kowk-Yung Yuen, Bin Du, Yu Hu, Jie Luo, Nanshan Zhong, Shao-qin Qiu, Shiyue Li, Jie Xiang |
| Rok vydání: |
2020 |
| Předmět: |
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| DOI: |
10.1101/2020.02.06.20020974 |
| Popis: |
BackgroundSince December 2019, acute respiratory disease (ARD) due to 2019 novel coronavirus (2019-nCoV) emerged in Wuhan city and rapidly spread throughout China. We sought to delineate the clinical characteristics of these cases.MethodsWe extracted the data on 1,099 patients with laboratory-confirmed 2019-nCoV ARD from 552 hospitals in 31 provinces/provincial municipalities through January 29th, 2020.ResultsThe median age was 47.0 years, and 41.90% were females. Only 1.18% of patients had a direct contact with wildlife, whereas 31.30% had been to Wuhan and 71.80% had contacted with people from Wuhan. Fever (87.9%) and cough (67.7%) were the most common symptoms. Diarrhea is uncommon. The median incubation period was 3.0 days (range, 0 to 24.0 days). On admission, ground-glass opacity was the typical radiological finding on chest computed tomography (50.00%). Significantly more severe cases were diagnosed by symptoms plus reverse-transcriptase polymerase-chain-reaction without abnormal radiological findings than non-severe cases (23.87% vs. 5.20%, PConclusionsThe 2019-nCoV epidemic spreads rapidly by human-to-human transmission. Normal radiologic findings are present among some patients with 2019-nCoV infection. The disease severity (including oxygen saturation, respiratory rate, blood leukocyte/lymphocyte count and chest X-ray/CT manifestations) predict poor clinical outcomes. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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