A case of unexplained mild Rh (D) haemolytic disease in utero
| Autor: | S. A. Walkinshaw, Imelda M. Bromilow, J. K. M. Duguid, C. R. Welch, I. Downing |
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| Rok vydání: | 1995 |
| Předmět: |
Adult
Erythrocytes Placenta Rh Isoimmunization Immunoglobulin G Erythroblastosis Fetal Pregnancy Humans Medicine Fetus Rh-Hr Blood-Group System biology Red Cell business.industry Histocompatibility Testing Infant Newborn Hematology Mononuclear phagocyte system Haemolysis medicine.anatomical_structure In utero Immunology biology.protein Female business |
| Zdroj: | Transfusion Medicine. 5:31-35 |
| ISSN: | 1365-3148 0958-7578 |
| DOI: | 10.1111/j.1365-3148.1995.tb00182.x |
| Popis: | This report describes the case of a patient with a history of HDN complicated by fetal losses, in which the alloantibody in this particular pregnancy did not appear to cause HDN in utero. No protective HLA-DR antibodies could be demonstrated, and transport of IgG across the placenta appeared to be normal. The infant's red cells possessed a normal D antigen and his mononuclear phagocyte system appeared unimpaired. However, the number of molecules of IgG bound in vivo per fetal red cell was below the level usually associated with significant haemolysis and HDN. |
| Databáze: | OpenAIRE |
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