Respiratory-gated time-of-flight PET/CT during whole-body scan for lung lesions: feasibility in a routine clinical setting and quantitative analysis
| Autor: | Ryohei Nakayama, Naohisa Suzawa, Masaki Ishida, Yoya Tomita, Hajime Sakuma, Yasutaka Ichikawa |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Respiratory-Gated Imaging Techniques medicine.medical_specialty Lung Neoplasms Time Factors Whole body imaging Standardized uptake value 030218 nuclear medicine & medical imaging Lesion Young Adult 03 medical and health sciences 0302 clinical medicine Positron Emission Tomography Computed Tomography Image Processing Computer-Assisted Humans Medicine Whole Body Imaging Radiology Nuclear Medicine and imaging Respiratory system Aged Aged 80 and over PET-CT Lung business.industry General Medicine Middle Aged medicine.anatomical_structure 030220 oncology & carcinogenesis Feasibility Studies Female Whole Body Scan sense organs Radiology medicine.symptom business Nuclear medicine Quantitative analysis (chemistry) |
| Zdroj: | Annals of Nuclear Medicine. 30:722-730 |
| ISSN: | 1864-6433 0914-7187 |
| DOI: | 10.1007/s12149-016-1118-3 |
| Popis: | To demonstrate the feasibility of respiratory gating during whole-body scan for lung lesions in routine 18F-FDG PET/CT examinations using a time-of-flight (TOF)-capable scanner to determine the effect of respiratory gating on reduction of both misregistration (between CT and PET) and image blurring, and on improvement of the maximum standardized uptake value (SUVmax). Patients with lung lesions who received FDG PET/CT were prospectively studied. Misregistration, volume of PET (Vp), and SUVmax were compared between ungated and gated images. The difference in respiratory gating effects was compared between lesions located in the upper or middle lobes (UML) and the lower lobe (LL). The correlation between three parameters (% change in misregistration, % change in Vp, and lesion size) and % change in SUVmax was analyzed. The study population consisted of 60 patients (37 males, 23 females; age 68 ± 12 years) with lung lesions (2.5 ± 1.7 cm). Fifty-eight out of sixty respiratory gating studies were successfully completed with a total scan time of 20.9 ± 1.9 min. Eight patients’ data were not suitable for analysis, while the remaining 50 patients’ data were analyzed. Respiratory gating reduced both misregistration by 21.4 % (p |
| Databáze: | OpenAIRE |
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