Increased frequency of ILT2-expressing CD56dimCD16+ NK cells correlates with disease severity of pulmonary tuberculosis

Autor:	Yanhua Liu, Zhai Fei, Yue Zheng, Xianghong Meng, Jing Jiang, Xiaoxing Cheng, Bingfen Yang, Xinjing Wang
Rok vydání:	2014
Předmět:	Adult Male Microbiology (medical) Tuberculosis Immunology Apoptosis chemical and pharmacologic phenomena Biology CD16 GPI-Linked Proteins Severity of Illness Index Microbiology Immunophenotyping Mycobacterium tuberculosis Interferon-gamma Young Adult Interleukin 21 Leukocyte Immunoglobulin-like Receptor B1 Antigens CD Lysosomal-Associated Membrane Protein 1 Predictive Value of Tests medicine Humans Interferon gamma Receptors Immunologic Tuberculosis Pulmonary Receptors IgG Sputum hemic and immune systems Middle Aged medicine.disease biology.organism_classification CD56 Antigen Coculture Techniques Killer Cells Natural Infectious Diseases Case-Control Studies Female K562 Cells Biomarkers Signal Transduction K562 cells medicine.drug
Zdroj:	Tuberculosis. 94:469-474
ISSN:	1472-9792
DOI:	10.1016/j.tube.2014.03.009
Popis:	The functional role of ILT2 in anti-tuberculosis immunity remains to be elucidated. In this study, we investigated expression and functions of ILT2 on NK cells during TB infection. The frequency of CD56(dim)CD16(+) NK cells that expressed ILT2 was significantly elevated in patients with active pulmonary TB as compared with tuberculin-positive healthy controls (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c571682f00359e340e8a64ffc486ffa5 https://doi.org/10.1016/j.tube.2014.03.009 Zobrazit plný text záznamu Full Text from ScienceDirect