Modulation of inner ear pressure in experimental endolymphatic hydrops☆, ☆☆, ★
Autor: | David Strelioff, James C. Andrews |
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Rok vydání: | 1995 |
Předmět: |
medicine.medical_specialty
Guinea Pigs Posture Audiology Internal medicine Pressure Animals Humans Medicine Endolymphatic Hydrops Inner ear Endolymphatic hydrops Meniere Disease Vestibular system Auditory dysfunction business.industry Labyrinthine Fluids Vestibular Function Tests medicine.disease Disease Models Animal medicine.anatomical_structure Otorhinolaryngology Ear Inner Vascular ischemia Auditory Perception Cardiology Surgery sense organs business |
Zdroj: | Otolaryngology - Head and Neck Surgery. 112:78-83 |
ISSN: | 0194-5998 |
DOI: | 10.1016/s0194-5998(95)70305-5 |
Popis: | Physiologic study of the guinea pig model of endolymphatic hydrops has been used to better understand the manifestations of Meniere's disease. Quantitative vestibular function testing demonstrates some changes in the hydrops subjects, especially if an additional stress such as postural inversion is imposed. Understanding the hydrodynamic changes on the endolymphatic and perilymphatic fluids by the hydrops condition as well as postural inversion may be useful in explaining the vestibular findings. These pressure effects may alter the micromechanics of the inner ear or possibly induce a relative vascular ischemia. Auditory dysfunction is speculated to occur through similar mechanisms. |
Databáze: | OpenAIRE |
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