Acute Myeloid Leukemia Case after Gene Therapy for Sickle Cell Disease

Autor:	Sunita Goyal, John Tisdale, Manfred Schmidt, Julie Kanter, Jennifer Jaroscak, Dustin Whitney, Hans Bitter, Philip D. Gregory, Geoffrey Parsons, Marianna Foos, Ashish Yeri, Maple Gioia, Sarah B. Voytek, Alex Miller, Jessie Lynch, Richard A. Colvin, Melissa Bonner
Rok vydání:	2022
Předmět:	Adult Carcinogenesis Sequence Analysis RNA Genetic Vectors Lentivirus Hematopoietic Stem Cell Transplantation Gene Expression Anemia Sickle Cell Genetic Therapy beta-Globins General Medicine Transplantation Autologous Leukemia Myeloid Acute Risk Factors Humans Female Transgenes
Zdroj:	New England Journal of Medicine. 386:138-147
ISSN:	1533-4406 0028-4793
DOI:	10.1056/nejmoa2109167
Popis:	Gene therapy with LentiGlobin for sickle cell disease (bb1111, lovotibeglogene autotemcel) consists of autologous transplantation of a patient's hematopoietic stem cells transduced with the BB305 lentiviral vector that encodes the β
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c569565a085a6ac43cd7ce4d2e7a40ac https://doi.org/10.1056/nejmoa2109167 Zobrazit plný text záznamu