Postinfectious onset in functional dyspepsia is a risk factor for weight loss
| Autor: | Jolien Schol, Florencia Carbone, Lieselot Holvoet, Karen Van den Houte, Esther Colomier, I.-Hsuan Huang, Emidio Scarpellini, Tim Vanuytsel, Jan Tack |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
Functional dyspepsia
Weight loss Science & Technology Gastroenterology & Hepatology Helicobacter pylori IRRITABLE-BOWEL-SYNDROME Gastroenterology GASTROINTESTINAL DISORDERS ASSOCIATION Postprandial Period HELICOBACTER-PYLORI INFECTION Gastroenteritis Abdominal Pain Risk Factors Weight Loss Humans Dyspepsia DUODENAL EOSINOPHILIA Life Sciences & Biomedicine |
| Zdroj: | Journal of Gastroenterology. 57:156-163 |
| ISSN: | 1435-5922 0944-1174 |
| Popis: | BACKGROUND: Functional dyspepsia (FD) is differentiated into two subgroups: the postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS). Acute gastroenteritis and Helicobacter pylori (HP) infection have been identified as risk factors for FD. It is unclear how these risk factors relate to Rome IV subgroups and their clinical impact. We aimed to study the association of postinfectious FD (PI-FD) and HP status with clinical profiles and weight loss. METHODS: Consecutive FD patients were assessed for symptom frequency and severity. Patients were identified as PDS, EPS or the overlap group according to severity scores. Additionally, PI history and HP status were determined. RESULTS: In a cohort of 459 FD-patients, 36% were characterized as having PDS, 9% as having EPS and 55% showed overlap. PI onset and positive HP status were reported by, respectively, 20% and 14% of patients, not significantly differing between subgroups (respectively, p = 0.31 and p = 0.40). Weight loss was reported by 63% in PDS, 36% in EPS and 56% in overlap patients (p = 0.011). Only early satiety severity correlated with more severe weight loss in the PDS (r 0.31, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink