Common Bean Leaves as a Source of Dietary Iron: Functional Test in an Iron-Deficient Rat Model
| Autor: | María Alejandra Mora-Avilés, Alejandro Blanco-Labra, Araceli Aguilera-Barreyro, Miriam Aracely Anaya-Loyola, Horacio Guzmán-Maldonado, Teresa García-Gasca, Mauricio Martínez-Zavala |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Erythrocytes Normal diet Anemia Hematocrit Ferrous Hemoglobins 03 medical and health sciences Animal science Leukocytes medicine Animals Ferrous Compounds Lymphocytes Rats Wistar Phaseolus Anemia Iron-Deficiency medicine.diagnostic_test biology food and beverages Complete blood count biology.organism_classification medicine.disease Rats Plant Leaves Ferritin Disease Models Animal 030104 developmental biology Biochemistry Chemistry (miscellaneous) Dietary Supplements Ferritins biology.protein Female Hemoglobin Biomarkers Iron Dietary Granulocytes Food Science |
| Zdroj: | Plant Foods for Human Nutrition. 71:259-264 |
| ISSN: | 1573-9104 0921-9668 |
| Popis: | Recent findings made by our group indicate that the iron content in Phaseolus vulgaris leaves is at least four times greater than in grains therefore, we evaluated the effect of supplementation with bean leaf (iron content of 275 mg/kg on a dry basis) in iron-deficient rats. Anemia was induced by feeding rats with an iron-deficient diet (IDD) for 11 days and iron-recovery diets were subsequently tested for 14 days using a normal diet, a 10 % bean leaf-supplemented IDD (BLSD) or a ferrous sulfate-supplemented IDD. Decreased levels of leukocytes (64 %), erythrocytes (30 %), lymphocytes (62 %), granulocytes (72 %), hematocrit (34 %), hemoglobin (35 %), and ferritin (34 %) were observed in the iron-deficient rats compared to the control rats. BLSD supplementation showed the highest recovery values relative to those recorded for control rats: leukocytes (40 %), erythrocytes (24 %), lymphocytes (33 %), granulocytes (88 %), hematocrit (17 %), and hemoglobin (18 %), suggesting that common bean leaves could be a good source of bioavailable iron with possible immunomodulatory effects. |
| Databáze: | OpenAIRE |
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