Asymptomatic bacteriuria and urinary tract infection in pregnant women with and without diabetes: Cohort study

Autor: Jan Jaap H. M. Erwich, Edwin R. van den Heuvel, Caroline Schneeberger, Suzanne E. Geerlings, Alewijn Ott, Ben W.J. Mol
Přispěvatelé: Reproductive Origins of Adult Health and Disease (ROAHD), APH - Quality of Care, Medical Microbiology and Infection Prevention, Amsterdam institute for Infection and Immunity, AII - Inflammatory diseases, Other departments, Infectious diseases, Stochastic Operations Research, Statistics
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Pregnancy in Diabetics
SDG 3 – Goede gezondheid en welzijn
Cohort Studies
0302 clinical medicine
Diabetes mellitus
Risk Factors
Pregnancy
Prenatal Diagnosis
Prevalence
Medicine
Prospective Studies
030212 general & internal medicine
Gestational/microbiology
Pregnancy Complications
Infectious
Prospective cohort study
First
Asymptomatic Infections
Infectious/diagnosis
Netherlands
Pregnancy Complications
Infectious/diagnosis
RISK
Diabetes
Gestational/microbiology
Urinary tract infection
OUTCOMES
030219 obstetrics & reproductive medicine
Obstetrics
Incidence
Incidence (epidemiology)
Diabetes
Pregnancy in Diabetics/microbiology
Obstetrics and Gynecology
Type 2/complications
female genital diseases and pregnancy complications
Practice Guidelines as Topic
Urinary Tract Infections
Gestation
Female
Pregnancy Trimester
Cohort study
Type 1/complications
Adult
medicine.medical_specialty
Bacteriuria
Pregnancy Trimester
Third
Asymptomatic Infections/epidemiology
Netherlands/epidemiology
Bacteriuria/complications
03 medical and health sciences
SDG 3 - Good Health and Well-being
Humans
EXPOSURE
Third
business.industry
Diabetes Mellitus
Type 2/complications
Urinary Tract Infections/complications
medicine.disease
Pregnancy Complications
Diabetes
Gestational
Pregnancy Trimester
First
Diabetes Mellitus
Type 1
Diabetes Mellitus
Type 2
Reproductive Medicine
Relative risk
Diabetes Mellitus
Type 1/complications
Small for gestational age
business
Asymptomatic bacteriuria
Follow-Up Studies
Zdroj: EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 222, 176-181. ELSEVIER SCIENCE BV
European journal of obstetrics, gynecology, and reproductive biology, 222, 176-181. Elsevier Ireland Ltd
European Journal of Obstetrics & Gynecology and Reproductive Biology, 222, 176-181. Elsevier
ISSN: 0301-2115
Popis: Objective: To compare the prevalence of asymptomatic bacteriuria (ASB) and the incidence of urinary tract infection (UTI) in pregnant women with and without diabetes mellitus (DM) or gestational DM (GDM).Study design: We performed a cohort study in five hospitals and two midwifery clinics in the Netherlands. Pregnant women with and without DM or GDM were screened for the presence of ASB around 12 and 32 weeks' gestation. Characteristics of participants as well as outcome data were collected from questionnaires and medical records. ASB was defined as the growth of at least 10e5 cfu/ml isolated from the urine of a woman without UTI complaints. UTI was considered to be present when a treating physician had diagnosed UTI and prescribed antibiotics.Results: We studied 202 women with and 272 women without DM or GDM. Of all women 31.7% with and 94.9% without DM or GDM provided a week 12 sample. The prevalence of ASB was comparable in women with and without DM or GDM (12 weeks' n = 322; 4.7% and 2.3%; relative risk (RR) 2.02; 95% confidence interval (CI) 0.52-7.84; 32 weeks' n = 422; 3.2% and 3.0%; RR 1.06; 95% CI 0.36-3.09), as was the incidence of UTI (16.8% and 12.9%; RR 1.31; 95% CI 0.85-2.02). Neither ASB nor UTI were associated with preterm birth or babies being small for gestational age.Conclusion: In pregnant women with and women without DM or GDM, the overall prevalence of ASB was low. Neither ASB nor UTI did differ significantly between the groups. Our data discourage a routine ASB screen and treat policy in pregnant women with DM or GDM. (C) 2017 Published by Elsevier Ireland Ltd.
Databáze: OpenAIRE
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