Mobile, Remote, and Individual Focused: Comparing Breath Carbon Monoxide Readings and Abstinence Between Smartphone-Enabled and Stand-Alone Monitors
| Autor: | Patrick A. Cato, Rachel L. Tomko, Erin A. McClure, Breanna M. Tuck, Joshua L. Karelitz, Jennifer Dahne |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male media_common.quotation_subject Original Investigations 030508 substance abuse 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Statistics Humans Medicine Cutoff 030212 general & internal medicine Bland–Altman plot Cotinine media_common Carbon Monoxide Smokers Receiver operating characteristic business.industry Smoking Public Health Environmental and Occupational Health Non-Smokers Gold standard (test) computer.file_format Abstinence United States Breath Tests ROC Curve chemistry Case-Control Studies ICO Female Smoking Cessation Smartphone 0305 other medical science business Breath carbon monoxide computer |
| Zdroj: | Nicotine Tob Res |
| ISSN: | 1469-994X |
| DOI: | 10.1093/ntr/ntaa203 |
| Popis: | Introduction Newly available, smartphone-enabled carbon monoxide (CO) monitors are lower in cost than traditional stand-alone monitors and represent a marked advancement for smoking research. New products are promising, but data are needed to compare breath CO readings between smartphone-enabled and stand-alone monitors. The purpose of this study was to (1) determine the agreement between the mobile iCO (Bedfont Scientific Ltd) with two other monitors from the same manufacturer (Micro+ pro and Micro+ basic) and (2) determine optimal, monitor-specific, cotinine-confirmed abstinence cutoff values. Methods Adult (≥18) smokers (n = 26) and nonsmokers (n = 21) provided three breath CO samples (using three different monitors) in each of 10 sessions, and urine cotinine was measured for gold standard determination of abstinence. CO comparisons (N = 437) were analyzed using regression-based Bland–Altman Analysis of Agreement; receiver operating characteristics curves were used to determine optimal abstinence cutoffs. Results Bland–Altman analyses indicated that the iCO monitor provided higher CO results than both Micro+ monitors. Sensitivity and specificity analyses showed that the optimal CO cutoff for determining abstinence was Conclusions Relative to both Micro+ monitors, the smartphone-enabled iCO provided systematically higher CO values and required a higher cutoff to reliably determine smoking abstinence. This does not indicate that CO values obtained using the iCO are not valid; instead, these results suggest that monitor-specific abstinence cutoffs are needed to ensure accurate bioverification of smoking status. Implications Results from this study indicate that CO values from the smartphone-enabled iCO should not be used interchangeably with the stand-alone Micro+ pro and Micro+ basic, particularly when lower CO values ( |
| Databáze: | OpenAIRE |
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