Clinical Utility of Fetal Short-lag Spatial Coherence Imaging
| Autor: | Kingshuk Roy Choudhury, Brita K. Boyd, Gregg E. Trahey, David Bradway, Dongwoon Hyun, P J McNally, Sarah Ellestad, Will Long |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
Acoustics and Ultrasonics Image quality Biophysics Second-harmonic imaging microscopy Signal-To-Noise Ratio 01 natural sciences Article Ultrasonography Prenatal 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Fetus Pregnancy Reference Values 0103 physical sciences Healthy volunteers Image Interpretation Computer-Assisted Image Processing Computer-Assisted Medicine Humans Radiology Nuclear Medicine and imaging 010301 acoustics Video based Radiological and Ultrasound Technology business.industry Channel data Reproducibility of Results Spatial coherence Sonographer Ultrasound imaging Female Nuclear medicine business |
| Popis: | In this study, we evaluate the clinical utility of fetal short-lag spatial coherence (SLSC) imaging. Previous work has documented significant improvements in image quality with fetal SLSC imaging as quantified by measurements of contrast and contrast-to-noise ratio (CNR). The objective of this study was to examine whether this improved technical efficacy is indicative of the clinical utility of SLSC imaging. Eighteen healthy volunteers in their first and second trimesters of pregnancy were scanned using a modified Siemens SC2000 clinical scanner. Raw channel data were acquired for routinely examined fetal organs and used to generate fully matched raw and post-processed harmonic B-mode and SLSC image sequences, which were subsequently optimized for dynamic range and other imaging parameters by a blinded sonographer. Optimized videos were reviewed in matched B-mode and SLSC pairs by three blinded clinicians who scored each video based on overall quality, target conspicuity and border definition. SLSC imaging was highly favored over conventional imaging with SLSC scoring equal to (28.2 ± 10.5%) or higher than (63.9 ± 12.9%) B-mode for video pairs across all examined structures and processing conditions. Multivariate modeling revealed that SLSC imaging is a significant predictor of improved image quality with p ≤ 0.002. Expert-user scores for image quality support the application of SLSC in fetal ultrasound imaging. |
| Databáze: | OpenAIRE |
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