What is the benefit of preoperative sperm preservation for patients who undergo restorative proctocolectomy for benign diseases?
| Autor: | C. W. Taat, Huug Obertop, J. F.M. Slors, L. T. Van Lochem, Gouke J. Bonsel, P. van Duijvendijk, J. W. A. De Vries |
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| Přispěvatelé: | Other departments |
| Rok vydání: | 2000 |
| Předmět: |
Adult
Male Retrograde ejaculation endocrine system medicine.medical_specialty medicine.medical_treatment Semen Semen analysis Anastomosis Sperm Preservation Colonic Diseases Semen quality fluids and secretions Humans Medicine Ejaculation Postoperative Period Cryopreservation Sperm Count medicine.diagnostic_test urogenital system business.industry Proctocolectomy Proctocolectomy Restorative Gastroenterology General Medicine medicine.disease Spermatozoa Semen cryopreservation Surgery Rectal Diseases Sperm Motility business |
| Zdroj: | Diseases of the colon and rectum, 43(6), 838-842. Lippincott Williams and Wilkins |
| ISSN: | 0012-3706 |
| DOI: | 10.1007/bf02238024 |
| Popis: | PURPOSE: In patients with benign colorectal diseases undergoing a restorative proctocolectomy with an ileal pouch-anal anastomosis, semen cryopreservation seems rational to enable the possibility of procreation in case surgery leads to sexual disorders or impotence. The aim of this study was to determine the preoperative and postoperative semen quality in patients undergoing ileal pouch-anal anastomosis. In addition, the study sought to determine the incidence of surgery-induced sexual dysfunction to evaluate the economic efficiency of semen cryopreservation as compared with alternatives such as microsurgical epididymal sperm aspiration. METHODS: Preoperative and postoperative semen analyses were offered to 97 patients with ileal pouch-anal anastomosis with benign colorectal diseases since 1989. The direct costs of the semen cryopreservation program were determined and compared with those of alternatives. RESULTS: In 34 of 40 consecutive patients with ileal pouch-anal anastomosis who made use of preoperative semen preservation, normal sperm concentrations, motility, and morphology were found. Mean semen characteristics of all 23 patients who returned for postoperative analysis were not different from preoperative values, but they were for total sperm number. Two patients developed temporary retrograde ejaculation postoperatively. None of the preserved semen samples was used, thus semen cryopreservation benefited none of these patients. The total costs of semen cryopreservation are between 2.2 and 5 times higher than the costs for one microsurgical epididymal sperm aspiration procedure. CONCLUSIONS: Preoperative semen cryopreservation in patients undergoing ileal pouch-anal anastomosis because of benign colorectal diseases is quite feasible. However, most likely because of improved surgical techniques and the increasing number of effective alternatives, preoperative semen cryopreservation in patients with ileal pouch-anal anastomosis is no longer cost effective. |
| Databáze: | OpenAIRE |
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