Pituitary Stalk Thickening and Primary Central Nervous System Lymphoma
| Autor: | Cynthia Hawkins, D Wherrett, S Weitzman, Peter B. Dirks, M Capra, Eric Bouffet |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Cancer Research
medicine.medical_specialty Pituitary gland Pathology Lymphoma B-Cell Biology Short stature Growth hormone deficiency Central Nervous System Neoplasms Posterior pituitary Internal medicine medicine Humans Child Growth Disorders Pituitary stalk Large-cell lymphoma Primary central nervous system lymphoma medicine.disease Magnetic Resonance Imaging medicine.anatomical_structure Endocrinology Neurology Oncology Growth Hormone Pituitary Gland Female Lymphoma Large B-Cell Diffuse Neurology (clinical) medicine.symptom Endocrine gland |
| Zdroj: | Journal of Neuro-Oncology. 67:227-231 |
| ISSN: | 0167-594X |
| DOI: | 10.1023/b:neon.0000021863.06620.48 |
| Popis: | We report a 14-year-old girl in whom a diagnosis of primary central nervous system lymphoma was confirmed while receiving growth hormone (GH) for GH deficiency, detected after presenting with short stature. MRI revealed an enhancing and thickened pituitary stalk with absence of the normal bright signal in the posterior pituitary. Regular MRI surveillance detected progression of the neurohypophyseal changes 13 months into GH treatment. Biopsy confirmed this to be B-cell large cell lymphoma. This case highlights the diagnostic and management challenges inherent in treating such children. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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