Lack of association between eNOS Glu298Asp gene polymorphism and carotid atherosclerosis in a Serbian population

Autor: Lazar Davidovic, Maša Umićević, Igor Koncar, Maja Zivkovic, Tamara Djurić, Dragan Alavantić, Dragan M. Vasic, Aleksandra Stanković
Rok vydání: 2009
Předmět:
Adult
Carotid Artery Diseases
Male
medicine.medical_specialty
Pathology
Genotype
Nitric Oxide Synthase Type III
Clinical Biochemistry
Population
Glutamic Acid
030204 cardiovascular system & hematology
Nitric oxide
Genomic disorders and inherited multi-system disorders [IGMD 3]
Molecular epidemiology [NCEBP 1]
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Gene Frequency
Enos
Internal medicine
medicine
Humans
Allele
Endothelial dysfunction
education
Aspartic Acid
education.field_of_study
Polymorphism
Genetic
biology
business.industry
Biochemistry (medical)
General Medicine
Middle Aged
medicine.disease
biology.organism_classification
medicine.anatomical_structure
Endocrinology
chemistry
Circulatory system
Female
Gene polymorphism
business
Serbia
030217 neurology & neurosurgery
Blood vessel
Zdroj: Clinical Chemistry and Laboratory Medicine, 47, 1573-5
Clinical Chemistry and Laboratory Medicine, 47, 12, pp. 1573-5
ISSN: 1437-4331
1434-6621
Popis: genepolymorphism.Endothelium-derived nitric oxide (NO), synthesizedbyendothelial NO synthase (eNOS), plays a crucial rolein regulating a wide variety of functions in the cardio-vascular system. A state of relative NO deficiency hasbeen linked to atherosclerosis, and has been equatedwith endothelial dysfunction (1).The
Databáze: OpenAIRE
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