Factors associated with muscle mass in community-dwelling older people in Singapore: Findings from the SHIELD study

Autor: Choon How How, C.Y.L. Tan, Dieu Thi Thu Huynh, Farah Safdar Husain, Menaka Yalawar, Samuel Teong Huang Chew, Magdalin Cheong, Wai Leng Chow, Geraldine E. Baggs, Ngiap Chuan Tan, Yen Ling Low, Siew Ling Tey, S.C. Kwan, Rebecca Hui San Ong
Rok vydání: 2019
Předmět:
Male
Sarcopenia
Physiology
Organic chemistry
Pathology and Laboratory Medicine
Body Mass Index
Cohort Studies
Elderly
0302 clinical medicine
Medicine and Health Sciences
Public and Occupational Health
030212 general & internal medicine
Vitamin D
Musculoskeletal System
Singapore
education.field_of_study
Multidisciplinary
Muscles
Organ Size
Vitamins
Physical sciences
Chemistry
Physiological Parameters
Cohort
Medicine
Female
Independent Living
Anatomy
Bioelectrical impedance analysis
Research Article
Cohort study
Science
Population
030209 endocrinology & metabolism
Chemical compounds
03 medical and health sciences
Signs and Symptoms
Diagnostic Medicine
Organic compounds
medicine
Humans
Muscle
Skeletal
education
Aged
Nutrition
business.industry
Body Weight
Malnutrition
Biology and Life Sciences
Physical Activity
Odds ratio
Anthropometry
medicine.disease
Skeletal Muscles
Age Groups
People and Places
Linear Models
Population Groupings
business
Body mass index
Demography
Zdroj: PLoS ONE
PLoS ONE, Vol 14, Iss 10, p e0223222 (2019)
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0223222
Popis: ObjectivesAging is associated with low muscle mass and has been linked to adverse health outcomes. The objectives of this cross-sectional study were: (1) to describe anthropometry, body composition, appendicular skeletal muscle mass index (ASMI; appendicular skeletal muscle mass/height2), and prevalence of low ASMI in older people with normal nutritional status (Malnutrition Universal Screening Tool score = 0); (2) to determine factors associated with ASMI, and odds ratios of having low ASMI.MethodsSHIELD is a study of community-dwelling older people aged 65 years and above in Singapore. ASMI was determined using bioelectrical impedance analysis and low ASMI was defined as ResultsA total of 400 older people (183 males and 217 females) took part in this study. The overall prevalence of low ASMI was 20.6% (15.5% in males and 24.9% in females). Females had significantly lower ASMI than males (P < 0.0001), age was inversely associated with ASMI (P = 0.0024) while BMI and calf circumference were positively associated with ASMI (both P < 0.0001) in the total cohort. In addition, ASMI was positively associated with bone mass in both genders (both P < 0.0001). After adjusting for covariates, the odds ratios of having low ASMI with every 1 year and 10 years increase in age were 1.13 (95% CI: 1.06, 1.20) and 3.36 (95% CI: 1.82, 6.21) respectively.ConclusionsThe high prevalence of low ASMI in community-dwelling older people with normal nutritional status highlights the need for early screening. There was a strong inverse association between age and ASMI while BMI, calf circumference and bone mass were positively associated with ASMI. These findings will give further weight to the importance and development of public health strategies in maintaining and improving muscle health in this population group.
Databáze: OpenAIRE
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