Forced expiratory volume in one second: A novel predictor of work disability in subjects with suspected obstructive sleep apnea
| Autor: | Marco Nardini, Elisa Maietti, Emanuela Vitali, Michela Schito, Valeria Casillo, Licia Ballerin, Francesco Stomeo, Piera Boschetto, Mariarita Stendardo |
|---|---|
| Přispěvatelé: | Stendardo M., Casillo V., Schito M., Ballerin L., Stomeo F., Vitali E., Nardini M., Maietti E., Boschetto P. |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
obesity Pulmonology Apnea Physiology Economics Social Sciences Excessive daytime sleepiness lcsh:Medicine population Blood Pressure Polysomnography Vascular Medicine absenteeism 0302 clinical medicine Quality of life Risk Factors Forced Expiratory Volume Surveys and Questionnaires Medicine and Health Sciences Respiratory Analysis lcsh:Science obstructive sleep apnea Sleep Apnea Obstructive Multidisciplinary medicine.diagnostic_test Epworth Sleepiness Scale Sleep apnea Middle Aged 030210 environmental & occupational health Bioassays and Physiological Analysis Neurology Italy Hypertension Female medicine.symptom management Research Article Employment Spirometry work disability medicine.medical_specialty Sleep Apnea ability multimorbidity Lung-function Socio-culturale Disorders of Excessive Somnolence Research and Analysis Methods scale 03 medical and health sciences epworth sleepiness association Internal medicine medicine Humans business.industry lcsh:R Biology and Life Sciences Odds ratio medicine.disease respiratory tract diseases Health Care Obstructive sleep apnea Dyspnea Cross-Sectional Studies 030228 respiratory system Labor Economics Quality of Life lcsh:Q Sleep Disorders Physiological Processes Sleep business |
| Zdroj: | PLoS ONE, Vol 13, Iss 7, p e0201045 (2018) PLoS ONE |
| Popis: | Whether the association of work disability with obstructive sleep apnea (OSA) is mainly due to the disease, i.e. the number and frequency of apneas-hypoapneas, or to coexisting factors independent from the disease, is not well-established. In this study, we aim to evaluate work ability in a group of subjects undergoing OSA workup and to identify the major contributors of impaired work ability. In a cross-sectional study, we enrolled 146 consecutive subjects who have been working for the last five years and referred to the sleep disorders outpatients’ clinic of the University-Hospital of Ferrara, Italy, with suspected OSA. After completing an interview in which the Work Ability Index (WAI) and the Epworth Sleepiness Scale (ESS) questionnaires were administered to assess work ability and excessive daytime sleepiness, respectively, subjects underwent overnight polysomnography for OSA diagnosing and spirometry. Of the 146 subjects, 140 (96%) completed the tests and questionnaires and, of these, 66 exhibited work disability (WAI < 37). OSA was diagnosed (apnea-hypopnea index 5) in 45 (68%) of the 66 subjects. After controlling for confounders, a lower level of forced expiratory volume at 1 second (FEV1), [odds ratio 0.97 (95% CI 0.95–1.00)], older age [1.09 (95% CI 1.03–1.15)], excessive daytime sleepiness [3.16 (95% CI 1.20–8.34)] and a worse quality of life [0.96 (95% CI 0.94–1.00)], but not OSA [1.04 (95% CI 0.41–2.62)], were associated with work disability. Patients with a higher number of diseases, in which OSA was not included, and a lower quality of life had an increased probability of absenteeism in the previous 12 months. In subjects with suspected OSA, FEV1 can be an important predictor of work disability. |
| Databáze: | OpenAIRE |
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