Socioeconomic status discrimination and C-reactive protein in African-American and White adults
Autor: | Miriam E. Van Dyke, Arshed A. Quyyumi, Sandra B. Dunbar, Tené T. Lewis, Viola Vaccarino, Priscilla Pemu, Gary H. Gibbons |
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Rok vydání: | 2017 |
Předmět: |
Adult
Male Gerontology Endocrinology Diabetes and Metabolism Population Social class White People Article Body Mass Index Education Cohort Studies 03 medical and health sciences Discrimination Psychological 0302 clinical medicine Endocrinology Risk Factors Humans 030212 general & internal medicine education Socioeconomic status Biological Psychiatry Inflammation Intersectionality education.field_of_study Depression Endocrine and Autonomic Systems Smoking Stressor Health Status Disparities Middle Aged United States Black or African American Psychiatry and Mental health C-Reactive Protein Social Class Socioeconomic Factors Cohort Female Self Report Psychology Body mass index Prejudice Stress Psychological 030217 neurology & neurosurgery Cohort study Demography |
Zdroj: | Psychoneuroendocrinology. 82:9-16 |
ISSN: | 0306-4530 |
Popis: | Objectives We examined the association between socioeconomic status (SES) discrimination and C-reactive protein (CRP) in a biracial cohort of middle-aged adults using an intersectionality framework. Methods Participants were 401 African-American and White adults from a population-based cohort in the Southeastern United States. SES discrimination was self-reported with a modified Experiences of Discrimination Scale, and CRP levels were assayed from blood samples. Linear regression analyses were used to examine the associations among SES discrimination, race, education, and CRP after controlling for age, gender, racial and gender discrimination, financial and general stress, body mass index, smoking, sleep quality, and depressive symptoms. Intersectional effects were tested using race × SES discrimination, education × SES discrimination and race × education × SES discrimination interactions. Results Adjusting for sociodemographics, racial discrimination, gender discrimination, and all relevant two-way interaction terms, we observed a significant race × education × SES discrimination interaction (p = 0.019). In adjusted models stratified by race and education, SES discrimination was associated with elevated CRP among higher educated African-Americans (β = 0.29, p = 0.018), but not lower educated African-Americans (β= −0.13, p = 0.32); or lower educated (β= −0.02, p = 0.92) or higher educated (β= −0.01, p = 0.90) Whites. Conclusions Findings support the relevance of SES discrimination as an important discriminatory stressor for CRP specifically among higher educated African-Americans. |
Databáze: | OpenAIRE |
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