Imaging techniques: new avenues in cancer gene and cell therapy
| Autor: | Amirhossein Sahebkar, Max Stanley Chartrand, Geir Bjørklund, Zahra Saadatpour, Hamed Ebrahimnejad, Badri Baghaei, Ali Rezaei, Hamid Morovati, Hamed Mirzaei, Hamid Reza Mirzaei |
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| Rok vydání: | 2016 |
| Předmět: |
Diagnostic Imaging
0301 basic medicine Cancer Research Pathology medicine.medical_specialty medicine.medical_treatment Cell- and Tissue-Based Therapy Disease Bioinformatics Cell therapy 03 medical and health sciences 0302 clinical medicine Neoplasms Biomarkers Tumor Animals Humans Medicine Combined Modality Therapy Molecular Biology medicine.diagnostic_test business.industry Cancer Genetic Therapy medicine.disease Molecular Imaging Radiation therapy Treatment Outcome 030104 developmental biology Positron emission tomography 030220 oncology & carcinogenesis Molecular Medicine Stem cell Molecular imaging business Biomarkers |
| Zdroj: | Cancer Gene Therapy. 24:1-5 |
| ISSN: | 1476-5500 0929-1903 |
| DOI: | 10.1038/cgt.2016.61 |
| Popis: | Cancer is one of the world's most concerning health problems and poses many challenges in the range of approaches associated with the treatment of cancer. Current understanding of this disease brings to the fore a number of novel therapies that can be useful in the treatment of cancer. Among them, gene and cell therapies have emerged as novel and effective approaches. One of the most important challenges for cancer gene and cell therapies is correct monitoring of the modified genes and cells. In fact, visual tracking of therapeutic cells, immune cells, stem cells and genetic vectors that contain therapeutic genes and the various drugs is important in cancer therapy. Similarly, molecular imaging, such as nanosystems, fluorescence, bioluminescence, positron emission tomography, single photon-emission computed tomography and magnetic resonance imaging, have also been found to be powerful tools in monitoring cancer patients who have received therapeutic cell and gene therapies or drug therapies. In this review, we focus on these therapies and their molecular imaging techniques in treating and monitoring the progress of the therapies on various types of cancer. |
| Databáze: | OpenAIRE |
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