Dataset on the epidemiology and genetic diversification of dengue virus (DENV) serotypes and genotypes in Mexico
| Autor: | Alvaro Diaz-Badillo, María de Lourdes Muñoz, Cesar Armando Brito-Carreón, Gerardo Pérez-Ramírez, Randy E. David, Ericel Hernández-García, Joel Navarrete-Espinosa, Miguel Moreno-Galeana, Eduardo Domínguez-de-la-Cruz |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Serotype
medicine.medical_specialty Epidemiology viruses Virulence Dengue virus Biology medicine.disease_cause lcsh:Computer applications to medicine. Medical informatics Dengue fever 03 medical and health sciences 0302 clinical medicine Phylogenetics Genotype medicine lcsh:Science (General) Phylogeny Evolutionary virology 030304 developmental biology Severe dengue Introduction of novel genotypes 0303 health sciences Multidisciplinary Phylogenetic tree virus diseases biochemical phenomena metabolism and nutrition medicine.disease Virology DENV genotypes DENV serotypes lcsh:R858-859.7 030217 neurology & neurosurgery Molecular Phylogenetics and Evolution lcsh:Q1-390 |
| Zdroj: | Data in Brief, Vol 32, Iss, Pp 106077-(2020) Data in Brief |
| ISSN: | 2352-3409 |
| Popis: | Dengue virus (DENV) evolution has had a significant impact on disease pathogenesis, virulence, and epidemiology in Mexico. Novel genotypic variation in DENV serotypes and genotypes may influence the magnitude and severity of dengue epidemics, as evidenced by 2009 data from Veracruz State. The data presented herein is related to the publication entitled "Epidemiological Implications of the Genetic Diversification of Dengue Virus (DENV) Serotypes and Genotypes in Mexico" [1]. Raw data and trees provide epidemiological data on DENV prevalence and a comprehensive phylogeny of both representative sequences collected from an NCBI repository, and 28 additional isolates from acute-phase plasma samples diagnosed with dengue fever or severe dengue (Raw sequencing data is hosted in the public repository Mendeley Data (http://dx.doi.org/10.17632/bf2kdhhf6x.2). Phylogenetic trees for each DENV serotype (DENV-1, -2, -3 and -4) were constructed using these sequences by a maximum likelihood methodology as well as a Bayesian Markov chain Monte Carlo (MCMC) integration approach. Phylogenetic trees exhibited: (1) DENV-1, genotype V, (2) the DENV-2 Asian/American and Asian II genotypes, (3) DENV-3, genotype III, and (4) DENV-4, genotype I. This data can be beneficial for future analyses on DENV serotype and genotype structure and the introduction of novel DENV genotype sequences in the Americas, for the further elucidation of dengue etiology. |
| Databáze: | OpenAIRE |
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