EMDataBank unified data resource for 3DEM
| Autor: | Steven J. Ludtke, John D. Westbrook, Matthew L. Baker, Wah Chiu, Ardan Patwardhan, Raul Sala, Eduardo Sanz Garcia, Corey F. Hryc, Grigore D. Pintilie, Gerard J. Kleywegt, Catherine L. Lawson, Ingvar Lagerstedt, Brian P. Hudson, Helen M. Berman |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Models
Molecular 0303 health sciences Databases Factual Macromolecular Substances 030302 biochemistry & molecular biology Proteins computer.file_format Biology Protein Data Bank Bioinformatics Pipeline (software) Data science Metadata Microscopy Electron 03 medical and health sciences Broad spectrum Imaging Three-Dimensional Resource (project management) Genetics Key (cryptography) EM Data Bank Database Issue Databases Protein computer 030304 developmental biology |
| Zdroj: | Nucleic Acids Research |
| ISSN: | 1362-4962 0305-1048 |
| DOI: | 10.1093/nar/gkv1126 |
| Popis: | Three-dimensional Electron Microscopy (3DEM) has become a key experimental method in structural biology for a broad spectrum of biological specimens from molecules to cells. The EMDataBank project provides a unified portal for deposition, retrieval and analysis of 3DEM density maps, atomic models and associated metadata (emdatabank.org). We provide here an overview of the rapidly growing 3DEM structural data archives, which include maps in EM Data Bank and map-derived models in the Protein Data Bank. In addition, we describe progress and approaches toward development of validation protocols and methods, working with the scientific community, in order to create a validation pipeline for 3DEM data. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|