Inappropriate secretion of antidiuretic hormone treated with frusemide
| Autor: | J C Demanet, F. Genette, Yves Waterlot, R Hallemans, Guy Decaux |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
medicine.medical_specialty
Potassium medicine.medical_treatment Sodium chemistry.chemical_element Diuresis Sodium Chloride Inappropriate ADH Syndrome Furosemide Internal medicine medicine Humans Salt intake General Environmental Science business.industry General Engineering General Medicine Endocrinology chemistry Chronic Disease General Earth and Planetary Sciences Diuretic business Hormone medicine.drug Antidiuretic Research Article |
| Zdroj: | British medical journal (Clinical research ed.). 285(6335) |
| ISSN: | 0267-0623 |
| Popis: | Seven out of nine patients with chronic inappropriate secretion of antidiuretic hormone were successfully treated with 40 mg frusemide daily. One patient needed 80 mg, and the remaining patient achieved only a small increase in diuresis after 40 mg frusemide; this was probably related to his low creatinine clearance. In order to maintain a salt intake high enough to compensate for the loss of urine electrolytes 3 to 6 g sodium chloride was added as tablets to the sodium-free diet in six patients. Hypokalaemia occurred in five patients but was easily corrected with either supplements of potassium chloride or a potassium-sparing diuretic. These findings add further weight to evidence that Frusemide is a good alternative for the treatment of patients with inappropriate secretion of antidiuretic hormone who cannot tolerate water restriction. |
| Databáze: | OpenAIRE |
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