Perfluoroalkyl and polyfluoroalkyl substances (PFASs): An optimized LC-MS/MS procedure for feed analysis
| Autor: | Arianna Stramenga, Tamara Tavoloni, Simone Bacchiocchi, Martina Ciriaci, Roberta Galarini, Massimiliano Giannotti, Arianna Piersanti, Tommaso Stecconi, Melania Siracusa |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Detection limit
Analyte Fluorocarbons Chromatography Food Safety Livestock Chemistry Animal feed Clinical Biochemistry Food Contamination Cell Biology General Medicine Repeatability Mass spectrometry Biochemistry Animal Feed Analytical Chemistry Commercial fish feed Matrix (chemical analysis) Tandem Mass Spectrometry Animals Humans Whole food Chromatography High Pressure Liquid Food Analysis |
| Zdroj: | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1186 |
| ISSN: | 1873-376X |
| Popis: | Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are extremely stable highly fluorinated aliphatic compounds, widely used in chemical and industrial applications since 1950s. They are ubiquitously detected in the environment and diet is the main route for human exposure. To ensure human safety, it is necessary to follow the whole food production chain, including animal feed. Still PFASs are not regulated as undesirable substances in feed, although several studies have shown they can be transferred from feed to livestock and thereafter to food. This paper describes the development, optimization and the full validation of a sensitive and reliable analytical protocol enabling the quantification of 19 PFASs in animal feeds by liquid chromatography - mass spectrometry (LC-MS/MS). The method was optimized, assessing the possible matrix interferences, and submitted to comprehensive validation (55 independent spiking experiments). Validation experiments were conducted on blank fish feed samples (natural levels of PFASs |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect