Salvage surgery for residual or recurrent laryngeal squamous cell carcinoma after (Chemo)radiotherapy: Oncological outcomes and prognostic factors

Autor: Alessandra Rinaldo, Vincent Vander Poorten, Luiz Paulo Kowalski, Elisabeth V. Sjögren, Jonathan J. Beitler, Juan P. Rodrigo, Cesare Piazza, Jeroen Meulemans, Robert P. Takes, Carl E. Silver, K. Thomas Robbins, Alfio Ferlito, Vinidh Paleri, Antti Mäkitie, Primož Strojan
Rok vydání: 2021
Předmět:
Microsurgery
medicine.medical_specialty
Neoplasm
Residual
Total laryngectomy
medicine.medical_treatment
Laryngectomy
Prognostic factors
03 medical and health sciences
All institutes and research themes of the Radboud University Medical Center
0302 clinical medicine
Robotic Surgical Procedures
Squamous cell carcinoma
Transoral robotic surgery
medicine
Humans
Oncological outcomes
Salvage surgery
Laryngeal carcinoma
Transoral laser microsurgery
030223 otorhinolaryngology
Laryngeal Neoplasms
Salvage Therapy
Chemo-radiotherapy
Chemotherapy
business.industry
Recurrent Laryngeal Squamous Cell Carcinoma
Conservation surgery
Chemoradiotherapy
General Medicine
Prognosis
3. Good health
Surgery
Radiation therapy
Oncology
030220 oncology & carcinogenesis
Carcinoma
Squamous Cell
Laser Therapy
Neoplasm Recurrence
Local
business
Rare cancers Radboud Institute for Health Sciences [Radboudumc 9]
Zdroj: European Journal of Surgical Oncology, 47, 11, pp. 2711-2721
European Journal of Surgical Oncology, 47, 2711-2721
EJSO-European Journal of Surgical Oncology, 47(11), 2711-2721. ELSEVIER SCI LTD
ISSN: 2711-2721
0748-7983
DOI: 10.1016/j.ejso.2021.05.035
Popis: Nonsurgical primary treatment of early and advanced laryngeal squamous cell carcinoma, employing radiotherapy with or without chemotherapy, is considered a standard of care in many centers throughout the world. When patients have persistent or recurrent disease after non-surgical treatment, salvage surgery is frequently the only remaining potentially curative treatment. Depending on the extent of the residual/recurrent disease, different surgical salvage options are at the surgeon's disposal. In selected cases with limited local disease, salvage transoral laser microsurgery, transoral robotic surgery and open partial laryngectomies can be employed to achieve cure while preserving laryngeal function. For more advanced cases total laryngectomy is necessary. Identifying situations with unacceptable results from surgical salvage may guide future therapies. (C) 2021 Elsevier Ltd, BASO similar to The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.
Databáze: OpenAIRE
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