Malignant hyperthermia in a liver transplant patient: a case report
| Autor: | B.P.A. Gonçalves, Cláudia Regina Fernandes, J.B.M. Vasconcelos, J.M. Gomes, José Huygens Parente Garcia, D.M. Azevedo, Gustavo Rego Coelho |
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| Rok vydání: | 2007 |
| Předmět: |
Male
medicine.medical_specialty Dantrolene Variable Expression Medicine Humans Intraoperative Complications Transplantation Isoflurane business.industry Muscle Relaxants Central Malignant hyperthermia Bilirubin Middle Aged medicine.disease Penetrance Surgery Liver Transplantation Treatment Outcome Anesthesia Anesthetics Inhalation Transplant patient business Complication Malignant Hyperthermia medicine.drug |
| Zdroj: | Transplantation proceedings. 39(10) |
| ISSN: | 0041-1345 |
| Popis: | Malignant hyperthermia is an autosomal dominant disorder with incomplete penetrance and variable expression. This syndrome is characterized by a hypermetabolic response to all commonly used inhalational anesthetics and depolarizing muscle relaxants. It can happen during or after the anesthesia. We describe a case of malignant hyperthermia during orthotopic liver transplantation. Our patient was a 48-year-old man, born in Brazil but with European ascendance, who developed malignant hyperthermia associated with the use of isoflurane. He was treated with dantrolene, which caused hepatic graft dysfunction. It is important that transplant teams be able to recognize and treat this complication. |
| Databáze: | OpenAIRE |
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