Metabolomics-assisted biotechnological interventions for developing plant-based functional foods and nutraceuticals
| Autor: | Neemisha Pathania, Dhananjay Dhokane, Liyao Ji, Arun Kumar, Shailesh Karre, Udaykumar Kage, Kareem A. Mosa, Deepa Madalageri |
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| Rok vydání: | 2017 |
| Předmět: |
0106 biological sciences
0301 basic medicine Databases Factual Phytochemicals Psychological intervention Health benefits Biology 01 natural sciences Industrial and Manufacturing Engineering 03 medical and health sciences Alkaloids Metabolomics Nutraceutical Genome editing Functional Food Humans Food research Terpenes business.industry Fatty Acids fungi Polyphenols food and beverages Plant based General Medicine Plants Plants Genetically Modified Biotechnology 030104 developmental biology Metabolite profiling Dietary Supplements business Genome Plant 010606 plant biology & botany Food Science |
| DOI: | 10.6084/m9.figshare.4736329.v2 |
| Popis: | Today, the dramatic changes in types of food consumed have led to an increased burden of chronic diseases. Therefore, the emphasis of food research is not only to ensure quality food that can supply adequate nutrients to prevent nutrition related diseases, but also to ensure overall physical and mental-health. This has led to the concept of functional foods and nutraceuticals (FFNs), which can be ideally produced and delivered through plants. Metabolomics can help in getting the most relevant functional information, and thus has been considered the greatest -OMICS technology to date. However, metabolomics has not been exploited to the best potential in plant sciences. The technology can be leveraged to identify the health promoting compounds and metabolites that can be used for the development of FFNs. This article reviews (i) plant-based FFNs-related metabolites and their health benefits; (ii) use of different analytic platforms for targeted and non-targeted metabolite profiling along with experimental considerations; (iii) exploitation of metabolomics to develop FFNs in plants using various biotechnological tools; and (iv) potential use of metabolomics in plant breeding. We have also provided some insights into integration of metabolomics with latest genome editing tools for metabolic pathway regulation in plants. |
| Databáze: | OpenAIRE |
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