Clinical Validation of a 3-Dimensional Ultrafast Cardiac Magnetic Resonance Protocol Including Single Breath-Hold 3-Dimensional Sequences
| Autor: | Gómez-Talavera, Sandra, Fernandez-Jimenez, Rodrigo, Fuster, Valentin, Nothnagel, Nils D, Kouwenhoven, Marc, Clemence, Matthew, García-Lunar, Inés, Gómez-Rubín, María C, Navarro, Felipe, Pérez-Asenjo, Braulio, Fernández-Friera, Leticia, Calero, María J, Orejas, Miguel, Cabrera, José A, Desco, Manuel, Pizarro, Gonzalo, Ibáñez, Borja, Sánchez-González, Javier, Nothnagel, Nils D., Gómez-Rubín, María C., Calero, María J., Cabrera, José A. |
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| Přispěvatelé: | Comunidad de Madrid, European Commission, Ministerio de Ciencia e Innovación (España), Universidad Carlos III de Madrid, Instituto de Salud Carlos III, European Research Council, Fundación ProCNIC |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
Magnetic Resonance Spectroscopy Intraclass correlation Imagen por resonancia magnética Contrast Media Gadolinium 030204 cardiovascular system & hematology FOV field of view 030218 nuclear medicine & medical imaging 0302 clinical medicine CMR cardiac magnetic resonance RVEDV right ventricular end-diastolic volume LVEF left ventricular ejection fraction Accelerated protocol Medicine Prospective Studies Tecnología médica Cardiac imaging Original Research ICC intraclass correlation coefficient Ejection fraction medicine.diagnostic_test LGE late gadolinium enhancement Contrast media Subtraction Heart Single breath Middle Aged RV right ventricle RVESV right ventricular end-systolic volume Magnetic resonance TFE turbo field echo cardiovascular system Female Cardiology and Cardiovascular Medicine RVEF right ventricular ejection fraction LVEDV left ventricular end-diastolic volume ESSOS Enhanced sensitivity encoding (SENSE) by Static Outer volume Subtraction Magnetic Resonance Imaging Cine heart magnetic resonance 03 medical and health sciences Imaging Three-Dimensional Medicina preventiva Predictive Value of Tests Gadolinio 3D 3-dimensional myocardium Humans Radiology Nuclear Medicine and imaging cardiovascular diseases Biología y Biomedicina Aged Sistema cardiovascular business.industry Myocardium Reproducibility of Results Magnetic resonance imaging Confidence interval CI confidence interval LV left ventricle 2D 2-dimensional LVESV left ventricular end-systolic volume business Cardiac magnetic resonance Nuclear medicine accelerated protocol |
| Zdroj: | Jacc. Cardiovascular Imaging e-Archivo. Repositorio Institucional de la Universidad Carlos III de Madrid instname Repisalud Instituto de Salud Carlos III (ISCIII) ABACUS. Repositorio de Producción Científica Universidad Europea (UEM) |
| Popis: | Objectives This study sought to clinically validate a novel 3-dimensional (3D) ultrafast cardiac magnetic resonance (CMR) protocol including cine (anatomy and function) and late gadolinium enhancement (LGE), each in a single breath-hold. Background CMR is the reference tool for cardiac imaging but is time-consuming. Methods A protocol comprising isotropic 3D cine (Enhanced sensitivity encoding [SENSE] by Static Outer volume Subtraction [ESSOS]) and isotropic 3D LGE sequences was compared with a standard cine+LGE protocol in a prospective study of 107 patients (age 58 ± 11 years; 24% female). Left ventricular (LV) mass, volumes, and LV and right ventricular (RV) ejection fraction (LVEF, RVEF) were assessed by 3D ESSOS and 2D cine CMR. LGE (% LV) was assessed using 3D and 2D sequences. Results Three-dimensional and LGE acquisitions lasted 24 and 22 s, respectively. Three-dimensional and LGE images were of good quality and allowed quantification in all cases. Mean LVEF by 3D and 2D CMR were 51 ± 12% and 52 ± 12%, respectively, with excellent intermethod agreement (intraclass correlation coefficient [ICC]: 0.96; 95% confidence interval [CI]: 0.94 to 0.97) and insignificant bias. Mean RVEF 3D and 2D CMR were 60.4 ± 5.4% and 59.7 ± 5.2%, respectively, with acceptable intermethod agreement (ICC: 0.73; 95% CI: 0.63 to 0.81) and insignificant bias. Both 2D and 3D LGE showed excellent agreement, and intraobserver and interobserver agreement were excellent for 3D LGE. Conclusions ESSOS single breath-hold 3D CMR allows accurate assessment of heart anatomy and function. Combining ESSOS with 3D LGE allows complete cardiac examination in Central Illustration |
| Databáze: | OpenAIRE |
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