Immunotherapy in Miscellaneous Medical Disorders Graves Ophthalmopathy, Asthma, and Regional Painful Syndrome

Autor: Romesh Khardori, Chaitanya Mamillapali, Michael Gonzales, Carmel Fratianni
Rok vydání: 2012
Předmět:
Zdroj: Medical Clinics of North America. 96:635-654
ISSN: 0025-7125
DOI: 10.1016/j.mcna.2012.04.013
Popis: In Graves ophthalmopathy, immunotherapy is offering an opportunity of reducing bad outcomes that lead to disfigurement and impairment of vision. These therapies are not perfect; however, we now have a chance to achieve better outcomes. In asthma, immune therapy using passive immunity targeting key proinflammatory cytokine/chemokines and medications of their effects has opened an avenue of research into a safe and durable therapy. Omalizumab appears to be safe and effective in clinical use. In regional pain syndrome, immune mechanisms may be involved in sustaining long-standing pain, and IVIG may moderate pain sensitivity by reducing immune activation.
Databáze: OpenAIRE