Multiple Micronutrient Supplementation Using Spirulina platensis during the First 1000 Days is Positively Associated with Development in Children under Five Years: A Follow up of A Randomized Trial in Zambia
| Autor: | Maureen Chitundu, Kazuya Masuda |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Pediatrics medicine.medical_specialty language skills Gross motor skill Zambia lcsh:TX341-641 malnutrition law.invention 03 medical and health sciences 0302 clinical medicine home-fortification Randomized controlled trial law medicine motor development 030212 general & internal medicine Early childhood Motor skill Spirulina (genus) 030109 nutrition & dietetics Nutrition and Dietetics Under-five biology business.industry personal–social skills medicine.disease Micronutrient biology.organism_classification Malnutrition the first 1000 days spirulina business lcsh:Nutrition. Foods and food supply Food Science |
| Zdroj: | Nutrients Volume 11 Issue 4 Nutrients, Vol 11, Iss 4, p 730 (2019) |
| ISSN: | 2072-6643 |
| DOI: | 10.3390/nu11040730 |
| Popis: | Early childhood development relies on various micronutrients. We recently reported that home fortification of complementary foods using spirulina reduced the time to attain motor milestones in Zambian infants. The objective of this study is to estimate the long-term associations between spirulina supplementation during the first 1000 days and child gross motor development, fine motor development, language, and personal&ndash social skills at preschool age. We used longitudinal data from a randomized trial conducted in Zambia. In 2015, 501 infants (age, 6&ndash 18 months) were provided daily supplements of maize-soy-based porridge with spirulina (SP) and without spirulina (CON). Supplementation period lasted for 16 months. In January 2018, children who participated in the initial trial were resurveyed (CON: 182 children SP: 188 children now aged 36&ndash 48 months). We assessed the infants&rsquo gross motor development, fine motor development, language, and personal&ndash social skills using a modified version of Malawi Development Assessment Tool. The initial clinical trial registration number was NCT03523182. Children in the SP group had higher scores in gross and fine motor development, language, and social skills than those in the CON group. Home fortification of complementary foods using spirulina during the first 1000 days improved development among Zambian children at preschool age. |
| Databáze: | OpenAIRE |
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