TYPICAL POLYPOIDAL CHOROIDAL VASCULOPATHY AND POLYPOIDAL CHOROIDAL NEOVASCULARIZATION
| Autor: | Se Woong Kang, Kunho Bae, Jun Won Jang, Jong Min Kim, Kyung-Tae Kim, Sang Jin Kim |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
0301 basic medicine medicine.medical_specialty Visual acuity genetic structures Fundus Oculi complex mixtures 03 medical and health sciences Polyps 0302 clinical medicine Fibrosis Ophthalmology medicine Humans Fluorescein Angiography Complete response Aged Retrospective Studies Aged 80 and over Choroid business.industry Follow up studies Retrospective cohort study Choroid Diseases General Medicine Middle Aged Macular degeneration medicine.disease Choroidal Neovascularization eye diseases 030104 developmental biology Choroidal neovascularization 030221 ophthalmology & optometry sense organs medicine.symptom business Tomography Optical Coherence Follow-Up Studies |
| Zdroj: | Retina. 39:1995-2003 |
| ISSN: | 0275-004X |
| Popis: | PURPOSE To compare typical polypoidal choroidal vasculopathy (T-PCV) and polypoidal choroidal neovascularization (P-CNV), which can be defined as two subtypes of PCV, and to elucidate the significance of the classification. METHODS Seventy-seven patients diagnosed with PCV and followed up for more than 12 months were reviewed. The PCV cases were divided into a T-PCV group (n = 36) and a P-CNV group (n = 41) according to the presence of features of pachychoroid or age-related macular degeneration. Angiographic and tomographic characteristics and changes in vision during the follow-up period were compared between the two groups. RESULTS Logarithm of the minimum angle of resolution visual acuity of T-PCV and P-CNV was 0.27 ± 0.31 and 0.62 ± 0.47 at baseline (P < 0.001) and 0.28 ± 0.41 and 0.54 ± 0.52 at the final visit (P = 0.006), respectively. A marginally higher rate of complete response to anti-vascular endothelial growth factor treatment was noted in the T-PCV group (47.2%) compared with the P-CNV group (26.8%) (P = 0.05). At the final visit, subfoveal fibrosis was noted in 11.1% of the T-PCV group and 39.0% of the P-CNV group (P = 0.009). CONCLUSION The two subtypes of PCV, P-CNV and T-PCV, behave differently in terms of angiographic and tomographic manifestations and visual outcomes. Classifying PCVs would be helpful not only for pathogenic implications, but also for prognostic significance. |
| Databáze: | OpenAIRE |
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