Relationship between neuropsychological behavior and brain white matter in first-episode psychosis
| Autor: | David J. Schretlen, Johnny Hsu, Anshel Kenkare, Jeffrey L. Crawford, Chenfei Ye, Akira Sawa, Andreia V. Faria |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Psychosis External capsule Article Cohort Studies White matter Young Adult 03 medical and health sciences 0302 clinical medicine Fractional anisotropy medicine Humans Cingulum (brain) Cognitive Dysfunction Biological Psychiatry Working memory Neuropsychology medicine.disease White Matter 030227 psychiatry Psychiatry and Mental health Diffusion Tensor Imaging medicine.anatomical_structure Psychotic Disorders Schizophrenia Female Psychology Neuroscience Insula 030217 neurology & neurosurgery |
| Zdroj: | Schizophr Res |
| ISSN: | 0920-9964 |
| DOI: | 10.1016/j.schres.2019.04.010 |
| Popis: | We addressed the relationship between white matter architecture, represented by MRI fractional anisotropy (FA), and cognition in individuals with first-episode psychosis (FEP) by applying for a new methodology that allows whole brain parcellation of core and peripheral white matter in a biologically meaningful fashion. Regionally specific correlations were found in FEP between three specific domains of cognition (processing speed, attention/working memory, and executive functioning) and FA at the deep (cerebral peduncles, sagittal striatum, uncinate, internal/external capsule, cingulum) and peripheral white matter (adjacent to inferior temporal, angular, supramarginal, insula, occipital, rectus gyrus). |
| Databáze: | OpenAIRE |
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