STD care in Zambia: an evaluation of the guidelines for case management through a syndromic approach

Autor: Stefan Hanson, E Sandstrom, J Kamanga, B Hojer, R M Sunkutu
Rok vydání: 1996
Předmět:
Zdroj: International journal of STDAIDS. 7(5)
ISSN: 0956-4624
Popis: Clinical diagnosis of STDs is unreliable and therefore constitutes a poor basis for choice of treatment. A syndromic approach has been suggested to increase effectiveness of treatment in resource poor settings. Algorithms for the treatment of STD syndromes were evaluated. A total of 436 patients were followed; cure rates were defined and estimated for genital ulcer disease (GUD), urethral and vaginal discharge. Cure rates for the discharge syndromes were high, 97-98%, for both sexes. The cure rate for GUD was 83% for female and 69% for male patients. A higher prevalence of syphilis in the female study population probably contributed to this. It is likely that a large proportion of the treatment failures were due to decreased susceptibility of Haemophilus ducreyi to trimethoprim-sulpha. The determination of cure rates met with a number of methodological problems. This makes it difficult to evaluate the algorithms as part of routine activities, as suggested earlier by WHO.
Databáze: OpenAIRE