Etiologic Agents of Bacteremia in the Early Period After Simultaneous Pancreas–Kidney Transplantation
| Autor: | Magdalena Durlik, K Kot, Artur Kwiatkowski, Dariusz Kawecki, Piotr Domagala, Andrzej Młynarczyk, Mirosław Luczak, Michal Wszola, Anna Sawicka-Grzelak, Jarosław Czerwiński, Andrzej Chmura, Grzegorz Michalak, Grażyna Młynarczyk, Monika Bieniasz, Wojciech Rowinski, Beata Sokół-Leszczyńska, Wojciech Lisik |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Methicillin-Resistant Staphylococcus aureus medicine.medical_specialty Staphylococcus Gram-positive bacteria Urinary system Bacteremia Gram-Positive Bacteria medicine.disease_cause Internal medicine Humans Medicine Postoperative Period Retrospective Studies Transplantation Candida glabrata biology business.industry Middle Aged Mycophenolic Acid biology.organism_classification Antimicrobial medicine.disease Kidney Transplantation Methicillin-resistant Staphylococcus aureus Anti-Bacterial Agents Surgery Catheter Female Pancreas Transplantation business Immunosuppressive Agents |
| Zdroj: | Transplantation Proceedings. 41:3151-3153 |
| ISSN: | 0041-1345 |
| DOI: | 10.1016/j.transproceed.2009.07.064 |
| Popis: | Background. Bacteremia is among the known complications in simultaneous pancreaskidney transplantation (SPKT). This study evaluated the frequency of microbial isolates and their susceptibility profiles among cultures of clinical samples obtained from blood and from the tips of blood vessel catheters of 26 SPKT recipients suspected of bacteremia in the early posttransplant period. Patients and Methods. Data on microbiologic blood cultures of 26 adult patients undergoing SPKT were collected prospectively from 2001 to the end of 2006. The isolation and identification of cultured microorganisms were performed according to standard microbiological procedures and commercially available tests. The susceptibility of the strains to antibacterial agents was established by the Clinical and Laboratory Standards Institute guidelines. Results. All patients were followed prospectively for the first 4 weeks after surgery. Among 66 clinical samples, there were 23 microbial isolates from blood samples of 17 recipients and catheter tips of 12 recipients. The most common isolates were Grampositive bacteria (73.9%) with domination of staphylococci (64.7%) and MRCNS strains (81.8%). Gram-negative bacteria comprised 17.4% of positive cultures, whereas yeast-like fungi, 8.7% with a predominance of Candida glabrata. Conclusion. Our study showed predominately Gram-positive bacteria in 73.9% of isolates. The increased proportion of multi-drug‐resistant bacteria and fungi to antimicrobial agents may be due to the frequent use of these agents for prophylaxis of bacterial infections in patients. |
| Databáze: | OpenAIRE |
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